Protein Alignment toe and Barhl2

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001005477.1
• Gene: Barhl2 / 104382
• MGIID: 1859314
• Length: 384
• Species: Mus musculus
• Alignment Length: 494
• Identity: 103/494 - (20%)
• Similarity: 157/494 - (31%)
• Gaps: 183/494 - (37%)

  Fly   140 SRFGLRGYDLAQHMLSQQGAVSKLLGTLRPPGLIGGSKPKV-----------ATPTVVSKIEQYK 193
            |.||:      ..:||..|:.|        ||::.|....:           |||:..|:|:
Mouse    10 SSFGI------DTILSGAGSGS--------PGMMNGDFRSLGEARTTDFRSQATPSPCSEID--- 57

  Fly   194 RENPTIFAWEIRERLITEGVCTNATAPSVSSINRILRNRAAERAAAEFARAASYGYAIHPTHPHP 258
                                 |..||||                       :.....:.|..||.
Mouse    58 ---------------------TVGTAPS-----------------------SPISVTLEPPEPHL 78

  Fly   259 YTSFPTWPAHHPLWGAVPLATPPGGGPAGAGGALQPGGS-------GSSYGSDGNMSSNPNSSNS 316
            .|.   .|.||..........||...||   .:|||...       .|:....|:.::.|.:|.|
Mouse    79 VTD---GPQHHHHLHHSQQPPPPSAVPA---QSLQPSPQQQPPPQPQSAAQQLGSAAAAPRTSTS 137

  Fly   317 --------------------NTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSR--DSR-S 358
                                :|:.|:.|:|..     ..|..:.....|.|..:.|..  |.| .
Mouse   138 SFLIKDILGDSKPLAACAPYSTSVSSPHHTPK-----QESNAAHESFRPKLEQEDGKTKLDKRED 197

  Fly   359 PDADAN-RMIDIEGEDSESQDSDQP-----KFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKL 417
            |.:|.. .....||:...:...:.|     |.|:.||.||..||::||:.|::..|..|..|..|
Mouse   198 PQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDL 262

  Fly   418 AARTALSEARVQVWFSNRRAKWRRHQRVNL----------IKQRDSPSTSSSPTPLVNPVVSPVS 472
            ||...|::.:|:.|:.|||.||:|...|.|          ..||..||
Mouse   263 AAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS----------------- 310

  Fly   473 PIPVPVPVAVPESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTINPGSKMSSKTSSVSSNQHMEEP 537
                              ||.|..|.:.:..|:::              ::..:::.|:.:...|
Mouse   311 ------------------PYFYHPSLLGSMDSTTA--------------AAAAAAMYSSMYRTPP 343

  Fly   538 AAAVATASPTASAPLSMG---GENSAFRALPMTLPMPMT 573
            |.......|.....|..|   |...|..  |::.|:|.|
Mouse   344 APHPQLQRPLVPRVLIHGLGPGGQPALN--PLSNPIPGT 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	20/100 (20%)
		Homeobox	388..440	CDD:278475	22/51 (43%)
Barhl2	NP_001005477.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		37/190 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..235		18/85 (21%)
		Homeobox	233..285	CDD:278475	22/51 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..384		6/19 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910