DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and prop1

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_004914810.1	Gene:	prop1 / 101734397	XenbaseID:	XB-GENE-22068967	Length:	242	Species:	Xenopus tropicalis

Alignment Length:	197	Identity:	64/197 - (32%)
Similarity:	100/197 - (50%)	Gaps:	26/197 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   382 PKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVN 446
            |..||:|||||.|||:.||..|.|:|||.:..||:||..|.|:|||:||||.|||||.|:|:|..
Frog    64 PTRRRHRTTFSQEQLEHLETAFSKNHYPDIYCREELAKITKLNEARIQVWFQNRRAKHRKHERTT 128

  Fly   447 LIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPESGQQKQPYPYSTSNMCNTSS-SSSNSQ 510
              ::...||:..:...|::.:.|...|             .::..||::.:::...|| ||:...
Frog   129 --QKSTVPSSMLTCGSLMSGMCSMSPP-------------SRQYQYPHALNHIPRFSSMSSAGYH 178

  Fly   511 PCNTIN----PGSKMSSKTSSVSSNQHMEEPAAAVATASPTASAPLSMGGENSAFRALPMTLPMP 571
            |.:.::    |.:....:.:...|.||.:...:..:.:||.|      |..:|.....|:|...|
Frog   179 PPSAVSQFTCPSNHPHLQPAGPPSRQHDDWYNSLRSISSPGA------GLSSSMITLTPVTALDP 237

  Fly   572 MT 573
            .|
Frog   238 ST 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	33/51 (65%)
prop1	XP_004914810.1	Homeobox	73..123	CDD:365835	30/49 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000