DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and drgx

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_004915967.1	Gene:	drgx / 100493837	XenbaseID:	XB-GENE-993712	Length:	263	Species:	Xenopus tropicalis

Alignment Length:	233	Identity:	75/233 - (32%)
Similarity:	111/233 - (47%)	Gaps:	47/233 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 GEDSESQDSD---QPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWF 432
            |..:.|:..|   :.|.|||||||:.:||:.||..|.::|||.|.|||:||.:..|:||||||||
Frog    18 GAHAASEFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWF 82

  Fly   433 SNRRAKWRRHQRVNLIKQ---RDSPSTSS-----SPTPLVNP--------------------VVS 469
            .|||||||:.:|.:..::   ..:|..::     ||:..|.|                    |.|
Frog    83 QNRRAKWRKTERGSCEQEGAKESAPEVTTAGRNLSPSSTVEPVRGKKETLEAQQRCLSHDRAVGS 147

  Fly   470 PVSPIPVPVPVAVPESGQQKQPYPYSTSNMCNTSSSSSNSQP--CNTINPGSKMSSKTSSVS--- 529
            ..|..|..:|.|:..:....|...:..|...:...|...|.|  .:.:.|....|.:|:||:
Frog   148 ATSFFPSCLPGALLNTASYAQALSHVASLKGSPLCSCCVSDPLGLSFLPPYGCQSHRTASVAALR 212

  Fly   530 --SNQHMEE--------PAAAVATASPTASAPLSMGGE 557
              :.:|.|.        |:|..:|.: :|||||..|.|
Frog   213 MKAREHSEAVLQSAQLLPSAGNSTGA-SASAPLEGGHE 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	32/51 (63%)
drgx	XP_004915967.1	Homeobox	38..91	CDD:395001	33/52 (63%)
drgx	XP_004915967.1	OAR	204..220	CDD:397759	4/15 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910