DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and LOC100485335

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_002938577.1	Gene:	LOC100485335 / 100485335	-ID:	-	Length:	281	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	81/250 - (32%)
Similarity:	116/250 - (46%)	Gaps:	46/250 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 GSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKE 402
            |....::.:......|.||......||..:|    :|:.:...:.|.:||||:|:.||::.||||
Frog    34 GQSNTTIDSCQQLDSSLDSEHQPGAANDDLD----ESQIRLQLKRKLQRNRTSFTQEQIEALEKE 94

  Fly   403 FDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSSSPTPLVNPV 467
            |:::|||.|..||:|||:..|.|||:|||||||||||||.::  |..||...|.:||...:.:..
Frog    95 FERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEK--LRNQRRQASNTSSHLSINSSF 157

  Fly   468 VSPV-SPIPVP---------VPVAVPESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTI----NPG 518
            .|.| ..||.|         ...|:..|.....|.|         |.:..|:.|...|    :..
Frog   158 SSSVYQSIPQPSNSGSMLGRSEAAITNSYGSLPPLP---------SFTMPNNLPIQPIASQTSTY 213

  Fly   519 SKMSSKTSSVS----------------SNQHMEEPA-AAVATASPTASAPLSMGG 556
            |.|.|.:.|||                |||::...| ::....||..|.|:.:.|
Frog   214 SCMISSSPSVSVRSYDAYTPPQLQTHMSNQNLGSGASSSTGLISPGVSVPVQVPG 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	33/51 (65%)
LOC100485335	XP_002938577.1	Homeobox	80..133	CDD:365835	34/52 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910