DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and arxb

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_002667096.1	Gene:	arxb / 100329907	ZFINID:	ZDB-GENE-121109-2	Length:	385	Species:	Danio rerio

Alignment Length:	322	Identity:	90/322 - (27%)
Similarity:	128/322 - (39%)	Gaps:	74/322 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 CTNATAPSVSSINRILRNRAAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLA 278
            |...|..|...|:.||..::.       .:.....:::.|.|||.:  .|. ....|.......:
Zfish    17 CKTPTLLSSYCIDSILGRKSP-------LKVQETPHSLWPLHPHMH--LPP-KLRRPFAPLTDSS 71

  Fly   279 TPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNT--NSGSG---CGDSSA- 337
            |....||.    .||.............:  |.:.:.|...|::..||  |...|   ||:::.
Zfish    72 TDETAGPR----LLQTACEKLKITEASIV--NISRAGSYQEHASCKNTPINEEEGADICGETNVT 130

  Fly   338 ----------GSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFS 392
                      .|...||.|                        |.|:| ....:.|.||.||||:
Zfish   131 LKQEREAFLKNSEETSLSA------------------------GSDTE-DGMLKRKQRRYRTTFT 170

  Fly   393 PEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTS 457
            ..||:|||:.|.|:|||.|.|||:||.|..|:||||||||.|||||||:.::|.:.....|...|
Zfish   171 SYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKVGVQPHTLSLHYS 235

  Fly   458 SSPTPLVNPVVSPVSPIP-VPVPVAVPESGQQKQPYPYSTSNMCNTSSSSSNSQPC-NTINP 517
            .:| |....:...:|..| ||.|....:|.   .|.|:...           :||. |:::|
Zfish   236 GAP-PAAQSLCHYLSGNPFVPNPHPAIDSA---WPAPFQRL-----------AQPAQNSVSP 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	5/15 (33%)
toe	NP_524041.2	Homeobox	388..440	CDD:278475	35/51 (69%)
arxb	XP_002667096.1	Homeobox	166..218	CDD:278475	35/51 (69%)
arxb	XP_002667096.1	OAR	351..368	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910