DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and hoxc3

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_002936696.1	Gene:	hoxc3 / 100190990	XenbaseID:	XB-GENE-5997986	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	323	Identity:	83/323 - (25%)
Similarity:	123/323 - (38%)	Gaps:	69/323 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 FPTWPAHHPLWGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMS------SNPNSSNSNTTH 320
            :|:...:.|     |...||.    .|.|:....|..|..|.|.::|      ..|.|.||::..
Frog    34 YPSEDDYQP-----PFCLPPD----TANGSASHKGEHSIKGIDFHLSEVSEQAQQPKSPNSDSPL 89

  Fly   321 SNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSP------------DADANRMIDIEGED 373
            ....:|.|   | .|...:|.:|....||:..|:.|..|            ::...:......:|
Frog    90 PKSASTQS---C-TSKKSTGPVSSDVTSPNKKSKGSNMPKQIFPWMKETRQNSKQKKQAPPPADD 150

  Fly   374 SESQDSD--QPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRR 436
            :.:.||.  ....:|.||.::..||.||||||..:.|.|...|.::|....|||.::::||.|||
Frog   151 APAVDSSFLSSASKRARTAYTNSQLVELEKEFHFNRYLCRPRRLEMAKLLNLSERQIKIWFQNRR 215

  Fly   437 AKWRRHQRVNLIKQRDSPSTSSSPTPLVNPVVSP-VSPIPVPVPVAVPESGQQKQPYPYSTSNMC 500
            .|::        |.........||..|     || .||..:|....:|..|......|.:|
Frog   216 MKFK--------KDHKGKGGGGSPGGL-----SPSSSPSLMPYSGNLPLDGDCGYEVPMAT---- 263

  Fly   501 NTSSSSSNSQPCNTINPGSKMSSKTSSVSSNQHMEEPAAAVATASPTASA----PLSMGGENS 559
                .:.|..|.|       |...|:  .|....|.|:|. ....|.:.|    |.||.|:|:
Frog   264 ----GAYNKSPGN-------MYGLTA--YSAPLFEGPSAQ-KRYGPQSLAPEYDPHSMQGDNN 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	23/51 (45%)
hoxc3	XP_002936696.1	Homeobox	167..220	CDD:395001	23/60 (38%)
hoxc3	XP_002936696.1	DUF4074	335..392	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910