Protein Alignment toe and pou5f3.2

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001123406.1
• Gene: pou5f3.2 / 100170181
• XenbaseID: XB-GENE-919841
• Length: 459
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 96/552 - (17%)
• Similarity: 151/552 - (27%)
• Gaps: 252/552 - (45%)

  Fly    62 GVGQPAAITPVSPTAATTVLAQPHSLSPSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAATN 126
            |:|.|                ||.|.:.|| :.::.            |.|...|.|..:|....
 Frog    30 GLGHP----------------QPFSFAFST-LKSEN------------GDSGVQGMGDCSAPVMP 65

  Fly   127 LNALASQHRLLELSRFGLRGYDLAQHMLSQQGAVSKLLGTLRPPGLIGGSKPKVATPTVV-SKIE 190
            .|::||         |...|    |...:|||      ..:|.|.         .|||:. |:|
 Frog    66 WNSMAS---------FDHHG----QVETNQQG------NPIRAPS---------PTPTLSDSRI- 101

  Fly   191 QYKRENPTIFAWEIRERLITEGVCTNATAPSVSSINRILRNRAAERAAAEFARAASYGYAIHPTH 255
                        :::|.:                        |.|..:.|.:....|     |:.
 Frog   102 ------------KVKEEV------------------------AHETDSGEESPEPKY-----PSP 125

  Fly   256 PHPYTSFP-TWPAHHPLWGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNS--- 316
            |:|...:| ||.. .|.|...|.|                       |::.| |:||..|.:
 Frog   126 PNPSLYYPNTWTG-SPFWQVNPTA-----------------------GNNSN-STNPMPSQTLVK 165

  Fly   317 ------NTTHSNGHNTN------------SGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADA 363
                  |||:....|.:            ..|.|..:::.:|.::..|.:..:|........:|.
 Frog   166 NGSLPGNTTYPTPANQSPNTPVDCVVSSMESSRCSSANSSNGAINERATTIPNGGMVDGGQSSDN 230

  Fly   364 NRMIDIEGE-------------------------------------------------------- 372
            ...:..|.|
 Frog   231 EEEVPSESEMEQFAKDLKHKRVSMGYTQADVGYALGVLYGKMFSQTTICRFESLQLSFKNMCQLK 295

  Fly   373 --------DSESQDS-----------DQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLA 418
                    ::|:.|:           .|.:.|:.||.........||..|.|...|......::|
 Frog   296 PFLERWLVEAENNDNLQELINREQVIAQTRKRKRRTNIENIVKGTLESYFMKCSKPGAQEMVQIA 360

  Fly   419 ARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSP-----STSSSP------------------ 460
            ....:.:..|:|||.|||.|.:| |.:..:.:.|..     .|.:||
 Frog   361 KELNMDKDVVRVWFCNRRQKGKR-QGMPTVDENDGEGYDVGQTMASPPVGHYSLPQVVTSQGYMA 424

  Fly   461 ------TPLVNPVVSPVSPIPVPVPVAVPESG 486
                  .||...........|.|:|.|:|..|
 Frog   425 APLGSTPPLYASAFHKNELFPQPLPHAMPMGG 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	14/96 (15%)
		Homeobox	388..440	CDD:278475	16/51 (31%)
pou5f3.2	NP_001123406.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..131		18/109 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..238		2/21 (10%)
		Pou	238..306	CDD:278582	1/67 (1%)
		Homeobox	329..382	CDD:278475	16/52 (31%)
		Mtc	<378..>440	CDD:296347	10/62 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910