DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and ventx3.2

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001123388.1	Gene:	ventx3.2 / 100170150	XenbaseID:	XB-GENE-483077	Length:	282	Species:	Xenopus tropicalis

Alignment Length:	230	Identity:	53/230 - (23%)
Similarity:	87/230 - (37%)	Gaps:	68/230 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 RLSLPALSPDSGSRDS----------RSP-------------DADANRMIDIEGEDSESQDS--- 379
            |:.||  :||...:::          |||             :...:|...||.....|.|.
Frog    49 RVILP--TPDYREKENYCGRNVHNGERSPPVRDQLHFHPAPQELTTSRRTSIEVSAESSTDQRVI 111

  Fly   380 -------------DQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVW 431
                         |:....|.||.|:.|||:||||.|.::.|...:.:.:|:....|||.:::.|
Frog   112 GMTDTNKKTKSVCDEDAASRARTKFTAEQLEELEKSFKENRYIGSSEKRRLSKVLKLSENQIKTW 176

  Fly   432 FSNRRAKWRRHQRVNLIK------------QRDSPS---TSSSPTPLVNPVVSPVSPIPV-PVPV 480
            |.|||.|::|..:...::            ..|.|:   :..|..|::.|.....|.||. |:..
Frog   177 FQNRRMKFKRQTQDARVEAFFSGLYLPYYGYPDLPTPGYSVQSEFPVLAPQTMAASSIPFGPLHS 241

  Fly   481 AVPESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTI 515
            .|...|....           ..|::..|.||:::
Frog   242 TVMSPGLHPA-----------IPSANLGSYPCSSM 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	22/51 (43%)
ventx3.2	NP_001123388.1	Homeobox	133..186	CDD:365835	22/52 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910