DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and rax

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_002936715.1	Gene:	rax / 100038124	XenbaseID:	XB-GENE-492665	Length:	326	Species:	Xenopus tropicalis

Alignment Length:	278	Identity:	91/278 - (32%)
Similarity:	118/278 - (42%)	Gaps:	55/278 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 LATPPGGGP-------AGAGGALQPG--GSGSSYGSDGNMSSNPNSSN-------SNTTHSNGHN 325
            |...|||.|       |..|.:.:..  ||..:..|..|.......|:       :...|....:
Frog    20 LLRSPGGNPSRLHSIEAILGFSKEDSVLGSFQTEVSPRNAKEVDKRSSRHCLHKMTEEIHPQQEH 84

  Fly   326 TNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQP--KFRRNR 388
            ...|...|.....||:.|...|||  |...|.:.|   |::         |.|..||  |.||||
Frog    85 LEDGQSDGYGDPYSGKTSSECLSP--GLSTSNNSD---NKL---------SDDEQQPKKKHRRNR 135

  Fly   389 TTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQR--VNLIKQR 451
            |||:..||.|||:.|:|||||.|.:||:||.:..|.|.||||||.||||||||.::  |..:|.:
Frog   136 TTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKLEVTSMKLQ 200

  Fly   452 DSP--STSSSPTPLVNPVVSPVSPI---------------PVPVPVAVPESGQQKQPYPYSTSNM 499
            |||  |.:.||.|.....:|...|:               .:|..|..|.|    .|..|:....
Frog   201 DSPILSFNRSPQPSAMSAISSSLPLDSWLTPSISNSTALQSLPGFVTSPPS----LPGSYTPPPF 261

  Fly   500 CNTSSSSSNSQPCNTINP 517
            .|.:|.....||...:.|
Frog   262 INPASVGHALQPLGAMGP 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	33/51 (65%)
rax	XP_002936715.1	Homeobox	135..188	CDD:365835	34/52 (65%)
rax	XP_002936715.1	OAR	299..315	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910