DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and LOC100008066

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_003199819.1	Gene:	LOC100008066 / 100008066	-ID:	-	Length:	251	Species:	Danio rerio

Alignment Length:	228	Identity:	63/228 - (27%)
Similarity:	85/228 - (37%)	Gaps:	62/228 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 PTWPAHHPLWGAVPLATPPGGGPAGAGGALQPGG----SGSSYGSDGNMSSNPNSSNSNTTHSNG 323
            |....|.||.|   ::....|...|...||.|||    ......:...||:.|
Zfish    38 PNIAPHVPLPG---VSLEESGRVFGVSSALLPGGVIRVPAHRPLAPAMMSAAP------------ 87

  Fly   324 HNTNSGSGC---GDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKFR 385
                  :.|   .|::....:..||||.|.:.:|....|                .|:...||.:
Zfish    88 ------ALCFPWMDNNRRFPKDRLPALIPFTVTRRIGHP----------------YQNRTPPKRK 130

  Fly   386 RNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRH-------- 442
            :.||:||..|:.||||.|.:..|.....|..||....:::|:|:.||.|||.||||.
Zfish   131 KPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAG 195

  Fly   443 ----QRVNLIKQRD------SPSTSSSPTPLVN 465
                .|:.|..|.|      |.|.||.|..|.|
Zfish   196 RQQANRMLLQLQADALQKSISESVSSDPLCLHN 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	22/51 (43%)
LOC100008066	XP_003199819.1	Homeobox	132..185	CDD:278475	22/52 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910