DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and cdx1b

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001092232.1	Gene:	cdx1b / 100004956	ZFINID:	ZDB-GENE-070615-29	Length:	255	Species:	Danio rerio

Alignment Length:	256	Identity:	72/256 - (28%)
Similarity:	106/256 - (41%)	Gaps:	53/256 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 PTHP-----HPYTSFPTWPAHHPLWGAVPLATPPGG------GPAGAGGALQPGGSGSSYGSDGN 306
            |.:|     |......|...||...|:...|.||..      ||          |||.|..|.|.
Zfish    35 PQYPDFTGYHHVPGITTNDPHHSQTGSWNPAYPPPREEWTPYGP----------GSGVSSSSTGQ 89

  Fly   307 MSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEG 371
            :..:|...:|..|          .|...||..|   |:..|||::   ..|:|.....|.:....
Zfish    90 LGFSPPEFSSVQT----------PGLLQSSINS---SVGQLSPNA---QRRNPYDWMRRSVPPAS 138

  Fly   372 EDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRR 436
            ...:::..|     :.|..::..|..||||||..|.|..:..:.:||...:|||.:|::||.|||
Zfish   139 SGGKTRTKD-----KYRVVYTDHQRLELEKEFHYSRYITIRRKAELATALSLSERQVKIWFQNRR 198

  Fly   437 AKWRRHQRVNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPES--GQQKQPYPYS 495
            ||.|:..:..:  |:..|:::::|||       |.|.:|..||:....|  |....|.|.|
Zfish   199 AKERKINKKKM--QQPQPASTTTPTP-------PGSALPGNVPMVTSSSSGGLVSPPMPMS 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	23/51 (45%)
cdx1b	NP_001092232.1	Caudal_act	13..132	CDD:282574	31/122 (25%)
cdx1b	NP_001092232.1	Homeobox	150..202	CDD:278475	23/51 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910