Protein Alignment ArfGAP1 and AGE2

DIOPT Version :10

• Sequence 1: NP_524040.2
• Gene: ArfGAP1 / 39417
• FlyBaseID: FBgn0020655
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_012220.3
• Gene: AGE2 / 854767
• SGDID: S000001306
• Length: 298
• Species: Saccharomyces cerevisiae
• Alignment Length: 333
• Identity: 81/333 - (24%)
• Similarity: 127/333 - (38%)
• Gaps: 100/333 - (30%)

  Fly     7 RRVLQELKPQDENSKCFECGTH-NPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMDKWKDI 70
            ::.|..|.....||.|.:|... :|:|.|.:.|::||::|:|.|||||.|:|.|:||.:|.||:.
Yeast     8 KKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWKEE 72

  Fly    71 ELEKM-KAGGNRNAREFLE----DQEDWNERAPITQRYNSKAAALYRDKIATLAQGKSW--DLKE 128
            .|.|: :...|..|..:.|    |:        :.||..:..::| ::.|....:.|.|  ||..
Yeast    73 HLVKLIQFKNNLRANSYYEATLADE--------LKQRKITDTSSL-QNFIKNKYEYKKWIGDLSS 128

  Fly   129 AQGRVGSNNSFSSGGSSNSSYQSRPSATGYGGNGGYQNGGGAEPGGYQQYQTQEFKDQKEEFFSR 193
            .:|...|........|:|.|..:..:......|            ..|:.|||
Yeast   129 IEGLNDSTEPVLHKPSANHSLPASNARLDQSSN------------SLQKTQTQ------------ 169

  Fly   194 RQVENASRPENLPPSQGGKYAGFGFTREPPPKTQSQELFDSTLSTLASGWSLFSTNASKLASTAK 258
                        |||.                         .|||..|..||.:...|.|:.|..
Yeast   170 ------------PPSH-------------------------LLSTSRSNTSLLNLQVSSLSKTTS 197

  Fly   259 EKAVTTVNLASTKIKEGTLLDSVQCGVTDVASKVTDMGKRGWNNLAGSNISSPQGGYNDPNFEDS 323
            ..:||:   ::|         |:....|...::|.:.|:|  |:|..|.:|.    |:.|    |
Yeast   198 NTSVTS---SAT---------SIGAANTKTGNRVGEFGQR--NDLKKSILSL----YSKP----S 240

  Fly   324 SAYQRSNS 331
            :..|..||
Yeast   241 AQTQSQNS 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap_ArfGap1	6..121	CDD:350059	37/119 (31%)
AGE2	NP_012220.3	COG5347	1..298	CDD:227651	81/333 (24%)