DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP1 and Agap2

DIOPT Version :9

Sequence 1:	NP_524040.2	Gene:	ArfGAP1 / 39417	FlyBaseID:	FBgn0020655	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_038935796.1	Gene:	Agap2 / 65218	RGDID:	628844	Length:	1304	Species:	Rattus norvegicus

Alignment Length:	141	Identity:	46/141 - (32%)
Similarity:	66/141 - (46%)	Gaps:	29/141 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMDKW-KDIELE 73
            :|.::....||.|.:||..||.|.|:..|..||:||||.||:||.|||.|||:.:|.| :::.|
  Rat   928 IQAIRNAKGNSTCVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTL- 991

  Fly    74 KMKAGGNRNAREF----------------LEDQEDWNERAPITQRYNSKAAALYRDKIATLAQ-- 120
            .:.|.||..|...                .|::|.|     |..:|..   .|:...:.|..:
  Rat   992 VLTAIGNDTANRVWESDTRGRAKPTRDSSREERESW-----IRAKYEQ---LLFLAPLGTTEEPL 1048

  Fly   121 GKS-WDLKEAQ 130
            |:. |...|||
  Rat  1049 GRQLWAAVEAQ 1059

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	40/120 (33%)
Agap2	XP_038935796.1	PRK07764	<37..174	CDD:236090
		Centaurin_gamma	401..560	CDD:133303
		PH_AGAP	668..908	CDD:241281
		ArfGap_AGAP	926..1033	CDD:350065	38/110 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900