Protein Alignment ArfGAP1 and Arfgap2

DIOPT Version :9

• Sequence 1: NP_524040.2
• Gene: ArfGAP1 / 39417
• FlyBaseID: FBgn0020655
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_006234592.1
• Gene: Arfgap2 / 362162
• RGDID: 1306177
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 129/527 - (24%)
• Similarity: 178/527 - (33%)
• Gaps: 194/527 - (36%)

  Fly     9 VLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMD-KWKDIEL 72
            :.:.|:....|..||:||..:|.|.|:|||:::|::|||.||||||||||:||..:| .|..::|
  Rat    13 LFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWSWLQL 77

  Fly    73 EKMKAGGNRNAREFLEDQ----EDWNERAPITQRYNSKAAALYRDKIATL--------------- 118
            ..|:.|||.||..|....    .|.|      .:|||:||.:||:||..|
  Rat    78 RCMQVGGNANATAFFRQHGCLANDAN------TKYNSRAAQMYREKIRQLGSTALARHGTDLWID 136

  Fly   119 ---------------------AQGKSWDLKE------------------AQGRVGSNNSF---SS 141
                                 .|..:||...                  ||...|.|...   |.
  Rat   137 NMNSAPSHSPEKKDSDFFTEHTQAPAWDTAATDPSGTQQPALPSESSSLAQPEPGPNTDLLGTSP 201

  Fly   142 GGSSNSSYQS----------RPSATGYGGNGGYQNGGGAEPG-GYQQYQTQEF------------ 183
            ..|..|.|.|          :.|..|.......:.|.||:.| |.|:...|.|
  Rat   202 QASLESMYLSAKGLSSTRELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSNQSFTEIERQAQVAEK 266

  Fly   184 ---------KDQKEE--------FFSRRQVENASRPENLPPSQGGK-----YAGFGFT------- 219
                     |.|.||        .:...|::.....:.|...:|.|     ..|.|..
  Rat   267 LREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSISH 331

  Fly   220 ----------REPPPKTQSQ----ELFDSTLSTLASG--------WSLFSTNASKLASTA----- 257
                      :|.|...:|.    :|||. :.|.|||        :||..|..|:..|.|
  Rat   332 SVLSEMQMIEQETPLSAKSSRSQLDLFDD-VGTFASGPPKYKDNPFSLGETFGSRWDSDAAWGMD 395

  Fly   258 ----KEKAVTTVNLASTKIKEGTLLDSVQCGVTDVASKVTDM-GKRGWNNLAGSN-ISSPQ--GG 314
                ||..||..::  ..|.|.|      ....:|.|:::.: ........||:. |||..  |.
  Rat   396 RVEEKEPEVTISSI--RPISERT------TSRREVESRISGLESSEARQKFAGAKAISSDMFFGR 452

  Fly   315 YNDPNFEDSSAYQRSNSVGGNLAGGLGQQSGVSDSDWGGWQDNGNSKSHMTSSSSYHNQLSSSSG 379
            ..|..:|..|..|:           |...|.:|.||..|                   .:..:.|
  Rat   453 EVDSEYEARSRLQQ-----------LSGSSAISSSDLFG-------------------DVDGAHG 487

  Fly   380 GGTASAG 386
            |||.|.|
  Rat   488 GGTVSLG 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	47/109 (43%)
Arfgap2	XP_006234592.1	PLN03114	12..484	CDD:178661	123/515 (24%)
		ArfGap	14..117	CDD:214518	47/108 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1155557at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910