DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP1 and Agap1

DIOPT Version :9

Sequence 1:	NP_524040.2	Gene:	ArfGAP1 / 39417	FlyBaseID:	FBgn0020655	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_038939665.1	Gene:	Agap1 / 316611	RGDID:	1309244	Length:	1428	Species:	Rattus norvegicus

Alignment Length:	163	Identity:	48/163 - (29%)
Similarity:	68/163 - (41%)	Gaps:	32/163 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASPRTRRVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMD 65
            :.|......||.::....||.|.:|.|.||.|.|:..|..:|:||||.||:||.|||.|||:.:|
  Rat  1174 LTSQSEAMALQSIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD 1238

  Fly    66 KWKDIELEKMKAGGNRNAREF----------------LEDQEDWNER--------API------- 99
            .|....::.|.:.||..|...                .|::|.|...        ||:
  Rat  1239 DWPMELIKVMSSIGNELANSVWEEGSQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCTEFSL 1303

  Fly   100 -TQRYNSKAAALYRDKIATLAQGKSWDLKEAQG 131
             .|..::.|....|..|..||.|...::.|..|
  Rat  1304 GQQLLHATAEEDLRTVILLLAHGSRDEVNETCG 1336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	41/138 (30%)
Agap1	XP_038939665.1	Centaurin_gamma	561..722	CDD:133303
		PH_AGAP	837..>911	CDD:241281
		PH-like	<1123..1163	CDD:418428
		ArfGap_AGAP2	1180..1288	CDD:350078	36/107 (34%)
		ANK repeat	1304..1332	CDD:293786	7/27 (26%)
		Ank_2	1307..1397	CDD:403870	8/30 (27%)
		ANK repeat	1339..1370	CDD:293786
		ANK repeat	1372..1397	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900