DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP1 and Acap1

DIOPT Version :9

Sequence 1:	NP_524040.2	Gene:	ArfGAP1 / 39417	FlyBaseID:	FBgn0020655	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001099266.2	Gene:	Acap1 / 287443	RGDID:	1305360	Length:	740	Species:	Rattus norvegicus

Alignment Length:	142	Identity:	42/142 - (29%)
Similarity:	67/142 - (47%)	Gaps:	31/142 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMDKWKDIEL 72
            :|..:::..|.|::|.:|....|:|.|:..||.:|::|||.|||||||.|.|||:|:|.|:...:
  Rat   406 QVAAQVQSVDGNAQCCDCKEPAPEWASINLGITLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELV 470

  Fly    73 EKMKAGGNRNAREFLEDQEDWNERAPITQRYNSKAAALYRDK---IATLAQGKSW---------- 124
            :.|...||                ..|.|.|.::..|:...|   ..:..:.::|
  Rat   471 KLMCELGN----------------VVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKF 519

  Fly   125 --DLKEAQGRVG 134
              .|.|.:||.|
  Rat   520 LTKLPEIRGRRG 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	35/105 (33%)
Acap1	NP_001099266.2	BAR_ACAP1	18..217	CDD:153323
		PH	266..360	CDD:278594
		PH_ACAP	268..364	CDD:270070
		ArfGap	406..519	CDD:279720	37/128 (29%)
		ANK repeat	575..602	CDD:293786
		ANK	<592..692	CDD:238125
		Ank_5	592..647	CDD:290568
		ANK repeat	606..637	CDD:293786
		Ank_5	626..680	CDD:290568
		ANK repeat	639..670	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900