Sequence 1: | NP_524040.2 | Gene: | ArfGAP1 / 39417 | FlyBaseID: | FBgn0020655 | Length: | 468 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_036228.1 | Gene: | APPL1 / 26060 | HGNCID: | 24035 | Length: | 709 | Species: | Homo sapiens |
Alignment Length: | 236 | Identity: | 44/236 - (18%) |
---|---|---|---|
Similarity: | 80/236 - (33%) | Gaps: | 67/236 - (28%) |
- Green bases have known domain annotations that are detailed below.
Fly 174 GYQQYQTQEFK-------DQKEEFFS---------RRQVEN--------------ASRPENLPPS 208
Fly 209 QGGKY---------AGFGFTREPPPK-----------TQSQELFDSTLSTLASGWSLFSTNASKL 253
Fly 254 ASTAKEKAVTTVNLASTKIKEGTLLDSVQ--------CGVTDVASKVTDMGKRGWNNLAGSNISS 310
Fly 311 PQGGYNDPNFED-------SSAYQRSNSVGGNLAGGLGQQS 344 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ArfGAP1 | NP_524040.2 | ArfGap | 7..114 | CDD:279720 | |
APPL1 | NP_036228.1 | Required for RAB5A binding | 1..428 | 40/227 (18%) | |
BAR_APPL1 | 20..234 | CDD:153315 | 10/31 (32%) | ||
BAR-PH_APPL | 252..376 | CDD:270067 | 21/125 (17%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 397..434 | 6/36 (17%) | |||
F&H | 403..414 | 1/10 (10%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 467..491 | ||||
PTB_APPL | 490..625 | CDD:269980 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 645..709 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |