Protein Alignment ArfGAP1 and Arfgap1

DIOPT Version :9

• Sequence 1: NP_524040.2
• Gene: ArfGAP1 / 39417
• FlyBaseID: FBgn0020655
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001361599.1
• Gene: Arfgap1 / 228998
• MGIID: 2183559
• Length: 424
• Species: Mus musculus
• Alignment Length: 505
• Identity: 178/505 - (35%)
• Similarity: 244/505 - (48%)
• Gaps: 126/505 - (24%)

  Fly     1 MASPRTRRVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMD 65
            |||||||:||:|::.||||:.|||||..|||||||||||||||||||:||.||||||||||||||
Mouse     1 MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 65

  Fly    66 KWKDIELEKMKAGGNRNAREFLEDQEDWNERAPITQRYNSKAAALYRDKIATLAQGKSWDLKEAQ 130
            |||||||||||||||...|||||.|:|:.....:..:|:|:||||:|||:||||:||.|.|:.:.
Mouse    66 KWKDIELEKMKAGGNAKFREFLETQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSP 130

  Fly   131 GR-----VGSNNSFSSGGSSNSSYQSRPSATGYGGNGGYQNGGGAEPGGYQQYQTQEFKDQKEEF 190
            .:     ......|::..:|     .:|.:....|:..:::....:.|.||..|
Mouse   131 AQNWTPPQPKTLQFTAHRAS-----GQPQSAAASGDKAFEDWLNDDLGSYQGAQ----------- 179

  Fly   191 FSRRQVENASRPENLPPSQGGKYAGFGFTREPPPKTQSQELFDSTLSTLASGWSLFSTNASKLAS 255
                        ||       :|.|||.|  .||:.:..:..::.:|:|.||||.|:|.|||.||
Mouse   180 ------------EN-------RYVGFGNT--VPPQKREDDFLNNAMSSLYSGWSSFTTGASKFAS 223

  Fly   256 TAKEKAV-----------------------------TTVNLASTKIKEGTLLDSVQCGVTDVASK 291
            .|||.|.                             ..:..|..|:|||.:.|.|..||:.:|||
Mouse   224 AAKEGATKFGSQASQKFWGYKQQSEPASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASK 288

  Fly   292 VTDMGKRGWNNLAGSNISSPQGGYNDPNFEDSS-------AYQRSNSVGGNLAGGLGQQSGVSDS 349
            |..:|.:||.::.         .:.....||||       :||  ||.|.|     .|.|.:..|
Mouse   289 VQGVGSKGWRDVT---------TFFSGKAEDSSDRPLEGHSYQ--NSSGDN-----SQNSNIDQS 337

  Fly   350 DWGGWQDNGNSKSHMTSSSSYHNQLSSSSGGGTASAGLTRDADWSGFEATNYQSSETSYQNASSG 414
            .|..:......|:...||.|                       |:..:|:..:.|..|:....||
Mouse   338 FWETFGSAEPPKAKSPSSDS-----------------------WTCADASTGRRSSDSWDVWGSG 379

  Fly   415 GSTARRNMKLQDTSQKLSEGFESLDVKSVKPKTATASSANKGTAEDDAWN 464
            .::..:|..        |:|:||.:..|.:.:......|...|| |:.|:
Mouse   380 SASNNKNSN--------SDGWESWEGASGEGRAKATKKAAPSTA-DEGWD 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	77/106 (73%)
Arfgap1	NP_001361599.1	ArfGap_ArfGap1	6..121	CDD:350059	84/114 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842647
Domainoid	1	1.000	164	1.000	Domainoid score	I3935
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	269	1.000	Inparanoid score	I3012
Isobase	1	0.950	-	0	Normalized mean entropy	S1735
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003790
OrthoInspector	1	1.000	-	-		oto94374
orthoMCL	1	0.900	-	-		OOG6_102808
Panther	1	1.100	-	-	LDO	PTHR46395
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1743
SonicParanoid	1	1.000	-	-		X3149
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.730