DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP1 and git-1

DIOPT Version :9

Sequence 1:	NP_524040.2	Gene:	ArfGAP1 / 39417	FlyBaseID:	FBgn0020655	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_509761.2	Gene:	git-1 / 181253	WormBaseID:	WBGene00008805	Length:	670	Species:	Caenorhabditis elegans

Alignment Length:	122	Identity:	30/122 - (24%)
Similarity:	49/122 - (40%)	Gaps:	7/122 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMDKWKDIELEKMKAGGNRN 82
            |..:|.:||....:|.||..|..||.||...|..||..:|::|.:....|.:..:..:.|....|
Worm    14 EQKECDDCGKKEVEWASVKKGTVICSECFCFHSYLGPSVSYLRHLRKSAWDEEHIRLVHALNTSN 78

  Fly    83 AREFLED---QEDWNERAPITQRYNSKAAALYRDKIATLA----QGKSWDLKEAQGR 132
            .....|.   :.....:.|:.|..:.......::|...|.    :||..||:.:..|
Worm    79 TNMIWESALYEGSTKFQKPMAQDPSHIKEQFVKEKYEKLTFQPKRGKDEDLENSLNR 135

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	23/98 (23%)
git-1	NP_509761.2	ArfGap	7..127	CDD:214518	27/112 (24%)
		ANK	<122..212	CDD:238125	5/14 (36%)
		Ank_5	152..207	CDD:290568
		ANK repeat	165..197	CDD:293786
		GIT	264..294	CDD:128828
		GIT	326..356	CDD:128828
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900