Protein Alignment ArfGAP1 and Agfg1

DIOPT Version :9

• Sequence 1: NP_524040.2
• Gene: ArfGAP1 / 39417
• FlyBaseID: FBgn0020655
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_006496493.1
• Gene: Agfg1 / 15463
• MGIID: 1333754
• Length: 577
• Species: Mus musculus
• Alignment Length: 507
• Identity: 104/507 - (20%)
• Similarity: 169/507 - (33%)
• Gaps: 179/507 - (35%)

  Fly     8 RVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLG-VHLSFVRSVTMDKWKDIE 71
            ::|:::.....|.|||:|....|.:|::|.|.::|..|||..|.|. .|.  |:|::|..:...|
Mouse    15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHR--VKSISMTTFTQQE 77

  Fly    72 LEKMKAGGNRNAREFLEDQEDWNERAPITQRYNSKAAAL--YRD--KIATLAQ----GKSWDLKE 128
            :|.::..||...::.      |      ...::.:::|:  :||  |:....|    .|.|.:..
Mouse    78 IEFLQKHGNEVCKQI------W------LGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPP 130

  Fly   129 AQGRVGSNNSFSSGGSSNSSYQSRP------SATGYGGNGGYQNGGGAEPGGYQQYQTQEFKDQK 187
            .|.:|.::...|..|||.||..|.|      |..|......:.|.|
Mouse   131 EQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGESAPALHLNKG------------------- 176

  Fly   188 EEFFSRRQVENASRPENLPPSQG---GKYAGFGFTREPPPKTQSQELFDSTLSTLASGWSLFSTN 249
                              .|||.   |:..|         :.|.::.|| .||.|.|  .:|:..
Mouse   177 ------------------TPSQSPVVGRSQG---------QQQEKKQFD-LLSDLGS--DIFAAP 211

  Fly   250 ASKLASTAKEKAVTTVNLASTKIKEGTLLDSVQCGVTDVASKVTDMGKRGWNNLAGSNISSPQGG 314
            |.:..:||
Mouse   212 APQSTATA--------------------------------------------------------- 219

  Fly   315 YNDPNFEDSSAYQRSNSVGGNLAG--GLGQQSGVSDSDWGGW----------QDNGNSKSHMT-- 365
             |..||...:::...||...:.|.  ..||.||  .|::||:          |..|.|...:.
Mouse   220 -NFANFAHFNSHAAQNSANADFANFDAFGQSSG--SSNFGGFPTASHSSFQPQTTGGSAGSVNAN 281

  Fly   366 ------------------SSSSYHNQLSSSSGGGTASAGL-TRDADWSGFEATNYQSSETSYQNA 411
                              |:|..|...|:.|...|..||| |.|...:.....|..|:.......
Mouse   282 FAHFDNFPKSSSADFGTFSTSQSHQTASTVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQG 346

  Fly   412 SSGGSTARRN----MKLQDTSQKLSEGFESL-DVKSVKPKTATASSANKGTA 458
            |..|:|.:..    :.:...|...|:.:.:| ::.||....||:|:|...|:
Mouse   347 SGFGTTGKAPVGSVVSVPSHSSASSDKYAALAELDSVFSSAATSSNAYTPTS 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	28/110 (25%)
Agfg1	XP_006496493.1	COG5347	8..268	CDD:227651	75/375 (20%)
		ArfGap_AGFG1	13..128	CDD:350082	32/126 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810