Protein Alignment ArfGAP1 and arfgap1

DIOPT Version :9

• Sequence 1: NP_524040.2
• Gene: ArfGAP1 / 39417
• FlyBaseID: FBgn0020655
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001123813.1
• Gene: arfgap1 / 100170564
• XenbaseID: XB-GENE-948122
• Length: 404
• Species: Xenopus tropicalis
• Alignment Length: 485
• Identity: 174/485 - (35%)
• Similarity: 242/485 - (49%)
• Gaps: 105/485 - (21%)

  Fly     1 MASPRTRRVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMD 65
            |||||||:||:|::.||||:.|||||..||||||||||||||||||||||.||||||||||||||
 Frog     1 MASPRTRKVLKEVRVQDENNTCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMD 65

  Fly    66 KWKDIELEKMKAGGNRNAREFLEDQEDWNERAPITQRYNSKAAALYRDKIATLAQGKSWDLKEAQ 130
            ||||:||||||.|||...|:|||.|:|::....:.::|||:||||||||:||||:|:.|.::.:.
 Frog    66 KWKDVELEKMKVGGNGKFRQFLEMQDDYDPCWSMQEKYNSRAAALYRDKVATLAEGRDWSVETSS 130

  Fly   131 GR---------VGSNNSFSSGGSSNSSYQSRPSATGYGGNG---GYQNGGGAEPGGYQQYQTQEF 183
            .|         :||::...|.||:.:...|...|.....|.   .||:||||
 Frog   131 ARNWTPPQPKMMGSSSVRPSAGSAQTGSSSGDKAFEDWLNDDMTSYQSGGGA------------- 182

  Fly   184 KDQKEEFFSRRQVENASRPENLPPSQGGKYAGFGFTREPPPKTQSQELFDSTLSTLASGWSLFST 248
                                   .:|..:|.|||.|..||.|  ..:..::.:::|.:|||.|:.
 Frog   183 -----------------------GNQENRYVGFGNTVNPPKK--EDDFLNNAMTSLYTGWSSFTV 222

  Fly   249 NASKLASTAKEKAVTTVNLASTKIKEGTLLDSVQCGVTDVASKVTDMGKRGWNNLAG-------- 305
            .|||.||.|||.|......|:.|:|:|.:||.|..||:.:|.||.....:||.::..
 Frog   223 GASKFASAAKESASKLGTQATQKVKDGRILDDVTSGVSHLAFKVQGASSKGWRDVTSFFSGKSED 287

  Fly   306 -SNISSPQGGYNDPNFEDSSAYQRSNSVGGNLAGGLGQQSGVSDSDWGGWQDNGNSKSHMTSSSS 369
             ...|:|:|||...|   ...||.: |.|.:.                 |:..|:|:.....|
 Frog   288 MGQSSAPEGGYQQGN---GDGYQNA-SYGKSF-----------------WETFGSSEEIKKPS-- 329

  Fly   370 YHNQLSSSSGGGTASAGLTRDADWSGFEATNYQSSETSYQNASSGGSTARRNMKLQDTSQKLSEG 434
                 .|.||.           .|:..|.:..:.|..|::...||.::..:|.. .|:.:.....
 Frog   330 -----KSPSGD-----------SWTFPENSTERKSSDSWEVWGSGTTSNNKNSN-SDSWENWDSH 377

  Fly   435 FESLDVKSVKPKTATASSANKGTAEDDAWN 464
            :::.:.|..|      ....|..|.:|.|:
 Frog   378 WDNTEGKGGK------KGGEKVPAAEDGWD 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	77/106 (73%)
arfgap1	NP_001123813.1	COG5347	2..265	CDD:227651	138/300 (46%)
		ArfGap_ArfGap1	6..121	CDD:350059	84/114 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3675
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	258	1.000	Inparanoid score	I3054
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1155557at2759
OrthoFinder	1	1.000	-	-		FOG0003790
OrthoInspector	1	1.000	-	-		oto104584
Panther	1	1.100	-	-	LDO	PTHR46395
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3149
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160