DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP1 and asap1

DIOPT Version :9

Sequence 1:	NP_524040.2	Gene:	ArfGAP1 / 39417	FlyBaseID:	FBgn0020655	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_031759002.1	Gene:	asap1 / 100036721	XenbaseID:	XB-GENE-1013472	Length:	1136	Species:	Xenopus tropicalis

Alignment Length:	139	Identity:	38/139 - (27%)
Similarity:	70/139 - (50%)	Gaps:	18/139 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TRRVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMDKWKDI 70
            |:.::.:::....|..|.:||:.:|.|:|...||..|:||||.||.:|||:|.::|:.:||....
Frog   441 TKAIIDDVQKTPGNEVCCDCGSPDPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDKLGTS 505

  Fly    71 ELEKMKAGGNRNAREFLED-----------------QEDWNERAPITQRYNSKAAALYRDKIATL 118
            ||...|..||.:..:.:|.                 ::::.....:.:|::.|..:...:|:..|
Frog   506 ELLLAKNVGNNSFNDIMEGNLLSPSAKPSPSSDMIARKEYITAKYVERRFSRKICSTGAEKLNEL 570

  Fly   119 AQG-KSWDL 126
            .:. ||.||
Frog   571 LEAVKSRDL 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	31/123 (25%)
asap1	XP_031759002.1	BAR_ASAP1	54..268	CDD:153325
		PH_ASAP	319..425	CDD:270071
		ArfGap_ASAP1	440..561	CDD:350073	32/119 (27%)
		Ank_2	585..660	CDD:403870
		ANK repeat	604..637	CDD:293786
		ANK repeat	639..670	CDD:293786
		PHA03247	<735..1052	CDD:223021
		SH3_ASAP1	1078..1134	CDD:212898
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910