DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oxsr1b and Pak

DIOPT Version :9

Sequence 1:	NP_957469.2	Gene:	oxsr1b / 394150	ZFINID:	ZDB-GENE-040426-723	Length:	520	Species:	Danio rerio
Sequence 2:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	114/279 - (40%)
Similarity:	159/279 - (56%)	Gaps:	23/279 - (8%)

- Green bases have known domain annotations that are detailed below.

Zfish    17 YELQEVIGSGATAVVQAAYCVPRKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTS 81
            |...|.||.||:..|..|.......:||||::||.: |...:.::.||..|.:..|||:|:|..|
  Fly   566 YTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQ-QPKKELIINEILVMRENKHPNVVNYLDS 629

Zfish    82 FVVKDELWLVMKLLSGGSVLDVIKHIISKGEHKTGVLDEPSIATVLKEVLQGLEYLHKNGQIHRD 146
            ::|.:|||:||:.|.|||:.||:...         .:||..||.|.:||||.||:||.|..||||
  Fly   630 YLVSEELWVVMEYLPGGSLTDVVTET---------CMDEGQIAAVCREVLQALEFLHANQVIHRD 685

Zfish   147 LKAGNILLGEDGSVQIADFGVSAFLATGGDMTRNKVRKTFVGTPCWMAPEVMEQVKGYDFKADIW 211
            :|:.|||||.||||::.|||..|.::     .....|.|.||||.||||||:.: |.|..|.|:|
  Fly   686 IKSDNILLGLDGSVKLTDFGFCAQIS-----PEQSKRTTMVGTPYWMAPEVVTR-KQYGPKVDLW 744

Zfish   212 SFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGITDKEMVKKYGKSLRKMISQCLQKEP 276
            |.||.|||:..|..||....|:|.|.|...|..|    .|.:|:   |...:.:..:.|||:.|.
  Fly   745 SLGIMAIEMVEGEPPYLNENPLKALYLIATNGKP----EIKEKD---KLSSAFQDFLDQCLEVEV 802

Zfish   277 EKRPTSSELLKHKFFQKAK 295
            ::|.::.:||||.|.:.|:
  Fly   803 DRRASALDLLKHPFLKLAR 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oxsr1b	NP_957469.2	STKc_OSR1_SPAK	15..291	CDD:270787	112/273 (41%)
oxsr1b	NP_957469.2	S_TKc	17..291	CDD:214567	112/273 (41%)
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	113/274 (41%)
		S_TKc	566..817	CDD:214567	112/273 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910