DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and CALN1

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_113656.2	Gene:	CALN1 / 83698	HGNCID:	13248	Length:	261	Species:	Homo sapiens

Alignment Length:	156	Identity:	43/156 - (27%)
Similarity:	66/156 - (42%)	Gaps:	35/156 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 ASSGSILPTEIPIEDEERLERIFNKLDRDGDGRIDIHDLSAALHEFGL--SSVYAEKFLQQSDKD 161
            |.|.|.....|.:|:.:.:...|..|||||:|.|...:|..|:...|.  |.|.....:|:.|.|
Human    65 AGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMD 129

  Fly   162 QSGNVGFAEFLHYVREHEKNLVLQFSHLDKNRDG----------------KVDLEE----LISAF 206
            ..|.|.|.||:..:   ...||     ..:.|||                ::.|||    |..||
Human   130 GDGQVDFDEFMTIL---GPKLV-----SSEGRDGFLGNTIDSIFWQFDMQRITLEELKHILYHAF 186

  Fly   207 KDLGLDIDMDEARNLLTRMDKDGSLN 232
            :|   .:.|.:..|::  ::::.|||
Human   187 RD---HLTMKDIENII--INEEESLN 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455	42/155 (27%)
		EFh	116..176	CDD:238008	21/61 (34%)
		EFh	186..242	CDD:238008	15/67 (22%)
		Mito_carr	285..370	CDD:278578
		Mito_carr	375..463	CDD:278578
		Mito_carr	470..581	CDD:278578
CALN1	NP_113656.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..39
CALN1	NP_113656.2	PTZ00184	74..>184	CDD:185504	32/117 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000