DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SCaMC and APC1

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_568940.1	Gene:	APC1 / 836303	AraportID:	AT5G61810	Length:	478	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	193/486 - (39%)
Similarity:	264/486 - (54%)	Gaps:	61/486 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 EERLERIFNKLDRDGDGRIDIHDLSAALHEFGLSSV-------YAEKFLQQSDKDQSGNVGFAEF 171
            |.|::::|...|....|.:|...:     |.||||:       ||..||:..|.::.|.|.:.||
plant    34 EIRIQKLFEFFDNSKLGFLDDTQI-----EKGLSSLSIPPKYRYASDFLKVCDSNRDGRVDYQEF 93

  Fly   172 LHYVREHEKNLVLQFSHLDKNRDGKVDLEELISAFKDLGLDIDMDEARNLLTRMDKDGSLNISFN 236
            ..|:...|..|...|..:|...:|.:...||..|....|:.|..:|..:.:..:|||.:..|:|.
plant    94 RRYMDAKELELYKIFQAIDIEHNGDICPAELWEALDKAGIKIKDEELASFMEHVDKDNNGIITFE 158

  Fly   237 EWRDFMLLAP-STDIHDLIKFWRHSTYLDIGEDMNVPDDFTQKEMQTGLWWRHLVAGGIAGAVSR 300
            |||||:||.| ...|.::...|.....:||||...:||..:....::.|    |:||||||||||
plant   159 EWRDFLLLNPHEATIENIYHHWERVCLIDIGEQAVIPDGISAHAQRSKL----LLAGGIAGAVSR 219

  Fly   301 TCTAPLDRIKVYLQVQTQRMGISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKR 365
            |.||||||:||.||||...:|:...:..:..|......:||||:||.|:|||:|.||||||.:|.
plant   220 TATAPLDRLKVALQVQRTNLGVVPTIKKIWREDKLLGFFRGNGLNVAKVAPESAIKFAAYEMLKP 284

  Fly   366 LIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLA--LRRTGQYAGIADAAVKIYK-- 426
            :|.|.||  .:....|..||..||.::||.||||:::||||.  :...|        ..|::|
plant   285 IIGGADG--DIGTSGRLLAGGLAGAVAQTAIYPMDLVKTRLQTFVSEVG--------TPKLWKLT 339

  Fly   427 -----QEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIAN--HDNNEQPSFLVLLACGSTS 484
                 |||.|:||||..|:::||:||||||||.|||||....|:  ||..| |..|:.|.||.||
plant   340 KDIWIQEGPRAFYRGLCPSLIGIIPYAGIDLAAYETLKDLSRAHFLHDTAE-PGPLIQLGCGMTS 403

  Fly   485 STLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGL 549
            ..||..|.|||.::|||:||.:::|...|:                      |.|.:|.|||.|.
plant   404 GALGASCVYPLQVIRTRMQADSSKTSMGQE----------------------FLKTLRGEGLKGF 446

  Fly   550 YRGITPNFLKVLPAVSISYVVYEYTSRALGI 580
            ||||.|||.||:|:.||||:|||...:.|.:
plant   447 YRGIFPNFFKVIPSASISYLVYEAMKKNLAL 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455	45/140 (32%)
		EFh	116..176	CDD:238008	20/66 (30%)
		EFh	186..242	CDD:238008	18/55 (33%)
		Mito_carr	285..370	CDD:278578	45/84 (54%)
		Mito_carr	375..463	CDD:278578	42/96 (44%)
		Mito_carr	470..581	CDD:278578	46/111 (41%)
APC1	NP_568940.1	FRQ1	32..168	CDD:227455	44/138 (32%)
APC1	NP_568940.1	PTZ00169	209..475	CDD:240302	137/298 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I2585
eggNOG	1	0.900	-	-		E1_KOG0036
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	306	1.000	Inparanoid score	I754
OMA	1	1.010	-	-		QHG55854
OrthoDB	1	1.010	-	-		D442523at2759
OrthoFinder	1	1.000	-	-		FOG0000464
OrthoInspector	1	1.000	-	-		otm3111
orthoMCL	1	0.900	-	-		OOG6_100689
Panther	1	1.100	-	-	LDO	PTHR24089
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X287
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.930