DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SCaMC and APC3

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_196349.1	Gene:	APC3 / 830623	AraportID:	AT5G07320	Length:	479	Species:	Arabidopsis thaliana

Alignment Length:	482	Identity:	185/482 - (38%)
Similarity:	265/482 - (54%)	Gaps:	49/482 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 EDEERLERIFNKLDRDGDGRIDIHDLSAALHEFGLSSV-------YAEKFLQQSDKDQSGNVGFA 169
            |.|.|:..:|:..|....|.:|...:     |.||:|:       ||....:..|.::.|.|.:.
plant    33 EREIRIRSLFDFFDNSNLGFLDYAQI-----EKGLASLQIPPEYKYARDLFRVCDANRDGRVDYQ 92

  Fly   170 EFLHYVREHEKNLVLQFSHLDKNRDGKVDLEELISAFKDLGLDIDMDEARNLLTRMDKDGSLNIS 234
            ||..|:...|..|...|..:|...:|.:..|||..|....|::||.:|....:..:|||.:..|:
plant    93 EFRRYIDAKELELYRIFQAIDVEHNGCILPEELWEALVKAGIEIDDEELARFVEHVDKDNNGTIT 157

  Fly   235 FNEWRDFMLLAP-STDIHDLIKFWRHSTYLDIGEDMNVPDDFTQKEMQTGLWWRHLVAGGIAGAV 298
            |.|||||:||.| ...:.::...|.....:||||...:||..::...::    |.|:|||:||||
plant   158 FEEWRDFLLLYPHEATLENIYHHWERVCLIDIGEQAVIPDGISKHVKRS----RLLLAGGLAGAV 218

  Fly   299 SRTCTAPLDRIKVYLQVQTQRMGISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQM 363
            |||.||||||:||.||||....|:...:..:..|......:||||:||:|:|||:|.||.|||.:
plant   219 SRTATAPLDRLKVVLQVQRAHAGVLPTIKKIWREDKLMGFFRGNGLNVMKVAPESAIKFCAYEML 283

  Fly   364 KRLIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRL--ALRRTGQYAGIADAAVKIYK 426
            |.:|.|:||  .:....|..||..||.::||.||||:::||||  .:...|:...:......|:.
plant   284 KPMIGGEDG--DIGTSGRLMAGGMAGALAQTAIYPMDLVKTRLQTCVSEGGKAPKLWKLTKDIWV 346

  Fly   427 QEGVRSFYRGYVPNILGILPYAGIDLAVYETLK---RRYIANHDNNEQPSFLVLLACGSTSSTLG 488
            :||.|:||:|..|::|||:||||||||.|||||   |.||.   .:.:|..|:.|:||.||..||
plant   347 REGPRAFYKGLFPSLLGIVPYAGIDLAAYETLKDLSRTYIL---QDTEPGPLIQLSCGMTSGALG 408

  Fly   489 QLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGLYRGI 553
            ..|.|||.:||||:||.:::|                      ||...|...::.|||.|.|||:
plant   409 ASCVYPLQVVRTRMQADSSKT----------------------TMKQEFMNTMKGEGLRGFYRGL 451

  Fly   554 TPNFLKVLPAVSISYVVYEYTSRALGI 580
            .||.|||:||.||:|:|||...:.:.:
plant   452 LPNLLKVVPAASITYIVYEAMKKNMAL 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455	45/142 (32%)
		EFh	116..176	CDD:238008	17/66 (26%)
		EFh	186..242	CDD:238008	20/55 (36%)
		Mito_carr	285..370	CDD:278578	44/84 (52%)
		Mito_carr	375..463	CDD:278578	41/92 (45%)
		Mito_carr	470..581	CDD:278578	43/111 (39%)
APC3	NP_196349.1	FRQ1	31..169	CDD:227455	44/140 (31%)
		PTZ00169	218..476	CDD:240302	125/284 (44%)
		Mito_carr	292..381	CDD:395101	41/90 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I2585
eggNOG	1	0.900	-	-		E1_KOG0036
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	306	1.000	Inparanoid score	I754
OMA	1	1.010	-	-		QHG55854
OrthoDB	1	1.010	-	-		D442523at2759
OrthoFinder	1	1.000	-	-		FOG0000464
OrthoInspector	1	1.000	-	-		otm3111
orthoMCL	1	0.900	-	-		OOG6_100689
Panther	1	1.100	-	-	O	PTHR24089
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X287
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840