DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SCaMC and slc25a42

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_009297217.1	Gene:	slc25a42 / 751743	ZFINID:	ZDB-GENE-060825-313	Length:	326	Species:	Danio rerio

Alignment Length:	293	Identity:	100/293 - (34%)
Similarity:	160/293 - (54%)	Gaps:	27/293 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 LVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMGISECMHIMLN---EGGSRSMWRGNGINVLKIA 350
            ||:|..||||::|..|||||.|:..||.:.|....|...::..   :.|..|:||||...::::.
Zfish    44 LVSGAFAGAVAKTAVAPLDRTKIIFQVSSNRFSAKEAYRLIYRTYLKDGFFSLWRGNSATMVRVI 108

  Fly   351 PETAFKFAAYEQMKRLI---RGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRTG 412
            |..|.:|.|:||.|.::   .|..| :.:..|.|..||:.||..:..|.||:::::.|:|:....
Zfish   109 PYAAIQFCAHEQYKGILGKYYGFQG-KALPPVPRLLAGSLAGTTAAIITYPLDMVRARMAVTPKE 172

  Fly   413 QYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNNEQPSFLVL 477
            .|:.|.|..|:|.::||:::.|||:.|.|||::||||:....|||||:.: |.......|.....
Zfish   173 MYSNIMDVFVRISREEGLKTLYRGFTPTILGVVPYAGLSFFTYETLKKTH-AEKTGRAHPFPYER 236

  Fly   478 LACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVR 542
            |..|:.:..:||..||||.:||.|:|....                 ..|: ..|:.|..|:||.
Zfish   237 LVFGACAGLIGQSASYPLDVVRRRMQTAGV-----------------TGHT-YSTVLGTMREIVA 283

  Fly   543 QEGLT-GLYRGITPNFLKVLPAVSISYVVYEYT 574
            :||:. |||:|::.|::|...||.||::.::.|
Zfish   284 EEGIVRGLYKGLSMNWVKGPIAVGISFMTFDLT 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	31/86 (36%)
		Mito_carr	375..463	CDD:278578	34/87 (39%)
		Mito_carr	470..581	CDD:278578	32/106 (30%)
slc25a42	XP_009297217.1	PTZ00169	35..302	CDD:240302	94/277 (34%)
		Mito_carr	39..129	CDD:278578	31/84 (37%)
		Mito_carr	134..220	CDD:278578	33/85 (39%)
		Mito_carr	230..322	CDD:278578	32/105 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940