DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and Slc25a16

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_780403.1	Gene:	Slc25a16 / 73132	MGIID:	1920382	Length:	332	Species:	Mus musculus

Alignment Length:	309	Identity:	100/309 - (32%)
Similarity:	158/309 - (51%)	Gaps:	42/309 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 WWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQT---QRMGISECMHIMLNEGGSRSMWRGNGINV 346
            |.|..:||||||..::|..|||||:||.||...   :.:|:...:..:..:.|...:::|||..:
Mouse    36 WLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGNGAMM 100

  Fly   347 LKIAPETAFKFAAYEQMKRLIR---GDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLAL 408
            ::|.|..|.:|.|:|..|..|.   |..|.     |.|..||:.||..:....||::|::.|||.
Mouse   101 IRIFPYGAIQFMAFEHYKTFITTKLGVSGH-----VHRLMAGSMAGMTAVICTYPLDVVRVRLAF 160

  Fly   409 RRTGQ--YAGIADAAVKIY-KQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKR---RY---IA 464
            :..|:  |:||..|...|| |:.|...||||.:|.|||:.||||:....:.|||.   .|   :.
Mouse   161 QVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALL 225

  Fly   465 NHDNNEQPSFLVL-----LACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSS 524
            ...:::.|:.|||     |.||..:..:.|..|||..:.|.|:|..|.           :| :..
Mouse   226 GRPSSDNPNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAV-----------LP-EFE 278

  Fly   525 DAHSGEETMTGLFRKIVRQEGL-TGLYRGITPNFLKVLPAVSISYVVYE 572
            ...:..|||    :.:..|.|: .|||||::.|:::.:|:.::::..||
Mouse   279 KCLTMRETM----KYVYGQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYE 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	31/90 (34%)
		Mito_carr	375..463	CDD:278578	37/96 (39%)
		Mito_carr	470..581	CDD:278578	30/109 (28%)
Slc25a16	NP_780403.1	Mito_carr	33..125	CDD:278578	31/88 (35%)
		Solcar 1	34..120		30/83 (36%)
		PTZ00169	36..330	CDD:240302	100/309 (32%)
		Solcar 2	128..216		37/92 (40%)
		Mito_carr	131..214	CDD:278578	34/82 (41%)
		Mito_carr	238..330	CDD:278578	27/102 (26%)
		Solcar 3	238..328		27/102 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940