DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and Slc25a42

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001007571.1	Gene:	Slc25a42 / 73095	MGIID:	1920345	Length:	318	Species:	Mus musculus

Alignment Length:	293	Identity:	93/293 - (31%)
Similarity:	162/293 - (55%)	Gaps:	31/293 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 LVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMGISECMHIM----LNEGGSRSMWRGNGINVLKI 349
            |::|.:|||:::|..|||||.|:..||.::|....|...::    ||| |..|:||||...::::
Mouse    37 LLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRLLYFTYLNE-GFLSLWRGNSATMVRV 100

  Fly   350 APETAFKFAAYEQMKRLIRGDDGSRQMSIV--ERFYAGAAAGGISQTIIYPMEVLKTRLALRRTG 412
            .|..|.:|:|:|:.||::....|.|..::.  .|..|||.||..:.::.||:::::.|:|:....
Mouse   101 IPYAAIQFSAHEEYKRILGHYYGFRGEALPPWPRLLAGALAGTTAASLTYPLDLVRARMAVTPKE 165

  Fly   413 QYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNNEQPSFLVL 477
            .|:.|....::|.::||:::.|.|:.|.:||::||||:....||:||..: ..:....||.....
Mouse   166 MYSNIFHVFIRISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKSLH-REYSGRPQPYPFER 229

  Fly   478 LACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEE--TMTGLFRKI 540
            :..|:.:..:||..||||.:||.|:|....                    :|.:  ::....|.|
Mouse   230 MVFGACAGLIGQSASYPLDVVRRRMQTAGV--------------------TGHQHGSILSTLRSI 274

  Fly   541 VRQEG-LTGLYRGITPNFLKVLPAVSISYVVYE 572
            ||:|| :.|||:|::.|:||...||.||:..::
Mouse   275 VREEGAVRGLYKGLSMNWLKGPIAVGISFTTFD 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	32/84 (38%)
		Mito_carr	375..463	CDD:278578	28/89 (31%)
		Mito_carr	470..581	CDD:278578	31/106 (29%)
Slc25a42	NP_001007571.1	Solcar 1	31..117		31/80 (39%)
		PTZ00169	34..295	CDD:240302	88/279 (32%)
		Solcar 2	129..214		28/84 (33%)
		Solcar 3	224..312		30/104 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940