DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and Dic1

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001287313.1	Gene:	Dic1 / 41640	FlyBaseID:	FBgn0027610	Length:	280	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	78/303 - (25%)
Similarity:	130/303 - (42%)	Gaps:	55/303 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   284 LWWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMGISECMHIMLNEGGSRSMWRGNGINVLK 348
            :|:    .||:|...:...|.|||.|||.||.|...:.:::.:..:..|.|....:.|...:||:
  Fly     9 MWF----FGGLASVGAAMVTHPLDLIKVTLQTQQGHLSVAQLIPKLAREQGVLVFYNGLSASVLR 69

  Fly   349 IAPETAFKFAAYEQMKRLIRGDDGSRQMSIVERFYAGAA--AGGISQTIIYPMEVLKTR------ 405
            ....:..:|..||..|:.:..|....::::     |||:  .|||..|   |.:::..|
  Fly    70 QLTYSTARFGVYEAGKKYVNTDSFGGKVAL-----AGASGLVGGIVGT---PADMVNVRMQNDVK 126

  Fly   406 LALRRTGQYAGIADAAVKIYKQEGVRSFYRG-YVPNILGILPYAGIDLAVYETLKRRYIAN--HD 467
            |..::...|....|..|::|:|||.:..:.| ......|||...| .:|.|:..|...:|.  ..
  Fly   127 LPPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIG-QIAFYDQTKIYLLATPYFQ 190

  Fly   468 NNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEET 532
            :|....|...|..|:.::||.|    ||.:::||                     |.:|..||
  Fly   191 DNLVTHFTASLVAGTIATTLTQ----PLDVLKTR---------------------SMNAKPGE-- 228

  Fly   533 MTGLFRKIVRQE---GLTGLYRGITPNFLKVLPAVSISYVVYE 572
            ..||: .||:..   |..|.::|..|.|:::.|...|::|..|
  Fly   229 FNGLW-DIVKHTAKLGPLGFFKGYVPAFVRLGPHTIITFVFLE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	23/84 (27%)
		Mito_carr	375..463	CDD:278578	25/96 (26%)
		Mito_carr	470..581	CDD:278578	27/106 (25%)
Dic1	NP_001287313.1	Mito_carr	10..92	CDD:278578	23/85 (27%)
		PTZ00169	13..273	CDD:240302	77/295 (26%)
		Mito_carr	89..184	CDD:278578	26/103 (25%)
		Mito_carr	189..278	CDD:278578	28/110 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930