DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and Dic4

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001262021.1	Gene:	Dic4 / 40039	FlyBaseID:	FBgn0036808	Length:	302	Species:	Drosophila melanogaster

Alignment Length:	310	Identity:	67/310 - (21%)
Similarity:	119/310 - (38%)	Gaps:	53/310 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 WWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMGISECMHIMLNEGGSRSMWRGNGINVLKI 349
            ||    .||.|........||:|.:|.::|:|.|:..|...:..:.:..|....:.|....:|:.
  Fly    23 WW----FGGFASMCVAFAVAPIDIVKTHMQIQRQKRSILGTVKRIHSLKGYLGFYDGFSAAILRQ 83

  Fly   350 APETAFKFAAYEQMKRLIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLAL------ 408
            ...|...|..|:..|::...|    :.|.:.:...|..||........|.:::..|:..
  Fly    84 MTSTNIHFIVYDTGKKMEYVD----RDSYLGKIILGCVAGACGSAFGIPTDLINVRMQTDMKEPP 144

  Fly   409 --RRTGQYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNNEQ 471
              ||  .|..:.|..::|.|:||.::.|:|....:..........:|.|:.:|.....|...|:.
  Fly   145 YKRR--NYKHVFDGLIRIPKEEGWKALYKGGSVAVFKSSLSTCSQIAFYDIIKTEVRKNISVNDG 207

  Fly   472 PSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGL 536
            .....|.:.|  :|.:....::||.:|||.:.                     ::..||
  Fly   208 LPLHFLTSLG--TSIISSAITHPLDVVRTIMM---------------------NSRPGE------ 243

  Fly   537 FRKIVRQE------GLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGI 580
            ||.:.:..      |:.|.|||..|..::..||.::.:|:||......||
  Fly   244 FRTVFQASVHMMRFGVMGPYRGFVPTIVRKAPATTLLFVLYEQLRLHFGI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	20/84 (24%)
		Mito_carr	375..463	CDD:278578	19/95 (20%)
		Mito_carr	470..581	CDD:278578	25/117 (21%)
Dic4	NP_001262021.1	PTZ00169	26..288	CDD:240302	63/296 (21%)
		Mito_carr	26..100	CDD:278578	18/73 (25%)
		Mito_carr	104..201	CDD:278578	20/102 (20%)
		Mito_carr	211..292	CDD:278578	23/109 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441961
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930