DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and MME1

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_609093.1	Gene:	MME1 / 33987	FlyBaseID:	FBgn0031881	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	85/307 - (27%)
Similarity:	130/307 - (42%)	Gaps:	40/307 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 RHLVAGGIAGAVSRTCTAPLDRIKVYLQV-------QTQR-MGISECMHIMLNEGGSRSMWRGNG 343
            :..:|||:.|..:.....|||.|||.||.       |..| .|:.:|........|.|..:||..
  Fly    16 KSFIAGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDCAARTFRYEGFRGFYRGIS 80

  Fly   344 INVLKIAPETAFKFAAYEQMKRLIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLAL 408
            ..::.:.|..|..||.|...|||.:.||..| ::..:.|.|||.||..|..:..|.:.:|..|..
  Fly    81 APLVGVTPIYAVDFAVYAAGKRLFQTDDHIR-LTYPQIFAAGALAGVCSALVTVPTDRIKVLLQT 144

  Fly   409 RRTGQ----YAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLK---RRYIANH 466
            :....    |.|..|.|.|:|:|.|:||.::|....||...| .|.....||.|:   |:..||.
  Fly   145 QTVSNGPLLYNGTIDTAAKLYRQGGIRSLFKGTCACILRDSP-TGFYFVTYEFLQELARKKSANG 208

  Fly   467 DNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEE 531
            ..:...:.|    .|.|:..:....:.|..::::|||:....|..:..|
  Fly   209 KISTTSTIL----SGGTAGIVFWTLAVPFDVLKSRLQSAPEGTYKHGIR---------------- 253

  Fly   532 TMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRAL 578
               .:||.::..||...|:|||.|..|:..|:.:..:...|.|:..|
  Fly   254 ---SVFRNLMATEGPKALFRGILPILLRAFPSTAAVFFGVELTNDLL 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	28/90 (31%)
		Mito_carr	375..463	CDD:278578	29/94 (31%)
		Mito_carr	470..581	CDD:278578	23/109 (21%)
MME1	NP_609093.1	Mito_carr	10..107	CDD:278578	28/90 (31%)
		Mito_carr	111..205	CDD:278578	30/95 (32%)
		Mito_carr	208..297	CDD:278578	22/111 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840