DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and SPAPB17E12.12c

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001018227.1	Gene:	SPAPB17E12.12c / 3361393	PomBaseID:	SPAPB17E12.12c	Length:	317	Species:	Schizosaccharomyces pombe

Alignment Length:	312	Identity:	83/312 - (26%)
Similarity:	147/312 - (47%)	Gaps:	43/312 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 LVAGGIAGAVSRTCTAPLDRIKVYLQVQTQR--MGISECMHIMLNEGGSRSMWRGNGINVLKIAP 351
            :::||:|..||||..:||:|:|:..|||..:  ..::..:..:.|..|....:||||.|.|:..|
pombe    24 MLSGGVAATVSRTAVSPLERMKIIFQVQNNKEYTSLTSTLVKIWNREGLIGFFRGNGTNCLRAFP 88

  Fly   352 ETAFKFAAYEQMKRLIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRTGQYA- 415
            ..|.:||.:..:|:....:...:.:...||...||.||..|....||:::.:|||::...|..:
pombe    89 YGAVQFATFNMLKQRALKNRSHQNLENHERLLFGAIAGAASCATTYPLDIARTRLSIETAGLTSR 153

  Fly   416 -----GIADAAVK-------------IYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRY 462
                 .:|:.::|             :..:.|..:.|.|....:|.::||..|....:|..|:::
pombe   154 SLAINNVANNSLKVKPLTLWSTLLYIVQHEGGYPALYNGLPATLLNVVPYVSICFFTFEFCKQKF 218

  Fly   463 IANHDNNE-QPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDA 526
            .:|.|... |..||     |..:..:||..::|..::|.|.|......|.:..:.    :||:..
pombe   219 FSNADLTAFQKLFL-----GGFTGIIGQTLTFPADVLRRRFQVNRIPGIGHNYKN----IKSAIF 274

  Fly   527 HSGEETMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRAL 578
            |            |.:.||:.|.:||.:.|.||::|.:||::..||..|:.|
pombe   275 H------------IYKTEGINGFFRGYSSNMLKIIPVMSITWYTYETVSKML 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	27/82 (33%)
		Mito_carr	375..463	CDD:278578	24/106 (23%)
		Mito_carr	470..581	CDD:278578	30/110 (27%)
SPAPB17E12.12c	NP_001018227.1	PTZ00169	17..295	CDD:240302	74/291 (25%)
		Mito_carr	21..101	CDD:278578	26/76 (34%)
		Mito_carr	111..221	CDD:278578	24/109 (22%)
		Mito_carr	223..316	CDD:278578	31/113 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940