DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SCaMC and Rim2

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_608615.1	Gene:	Rim2 / 33350	FlyBaseID:	FBgn0031359	Length:	365	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	87/364 - (23%)
Similarity:	137/364 - (37%)	Gaps:	108/364 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 HLVAGGIAGAVSRTCTAPLDRIKVYLQVQT----------------------------QR----- 319
            ||:|||.||.|....|.||:.:|..||..|                            ||
  Fly    11 HLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANGGQSELLRPEQRRKLST 75

  Fly   320 ------------------MGISEC----------------MHIMLNEGGSRSMWRGNGINVLKIA 350
                              |.||.|                .||:.|| |.|::::|.|.|::.:|
  Fly    76 TILRNRSQPQVIGGVRRIMAISHCGISSTTPKSMSIVQCLRHIVQNE-GPRALFKGLGPNLVGVA 139

  Fly   351 PETAFKFAAYEQMKRLIRGDDGSRQMSIVER------FYAGAAAGGISQTIIYPMEVLKTRLALR 409
            |..|..|..|.|.|..:      ..:..|||      ..:.|:||.:|.|...|:..:|||:.|.
  Fly   140 PSRAIYFCTYSQTKNTL------NSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQLD 198

  Fly   410 RTGQ-YAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANH-----DN 468
            ...: ...:.....::|.|.||.:||:|...:..||.. ..:...:||.:|.:.:...     |.
  Fly   199 YNSKVQMTVRQCIERVYAQGGVAAFYKGITASYFGICE-TMVHFVIYEFIKSKLLEQRNQRHTDT 262

  Fly   469 NEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETM 533
            .....||..:..|:.|.|:....:||..:.||||:.:                 .:..:|..:|:
  Fly   263 KGSRDFLEFMMAGAVSKTIASCIAYPHEVARTRLREE-----------------GNKYNSFWQTL 310

  Fly   534 TGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYE 572
                ..:.::||..|||||:....::.:|..:|....||
  Fly   311 ----HTVWKEEGRAGLYRGLATQLVRQIPNTAIMMATYE 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	37/148 (25%)
		Mito_carr	375..463	CDD:278578	25/94 (27%)
		Mito_carr	470..581	CDD:278578	24/103 (23%)
Rim2	NP_608615.1	Mito_carr	8..156	CDD:278578	37/145 (26%)
		Mito_carr	163..253	CDD:278578	24/90 (27%)
		Mito_carr	268..355	CDD:278578	24/99 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840