DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and slc25a16

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_991112.1	Gene:	slc25a16 / 324578	ZFINID:	ZDB-GENE-030131-3299	Length:	321	Species:	Danio rerio

Alignment Length:	315	Identity:	96/315 - (30%)
Similarity:	159/315 - (50%)	Gaps:	42/315 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 WWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQT---QRMGISECMHIMLNEGGSRSMWRGNGINV 346
            |.|...|||:||..:::..|||||:|:.||.|.   :.:|:...:..:..:.|...:::|||..:
Zfish    25 WLRSFTAGGVAGCCAKSTIAPLDRVKILLQAQNPHYKHLGVFATLKAVPKKEGFLGLYKGNGAMM 89

  Fly   347 LKIAPETAFKFAAYEQMKRLIR---GDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLAL 408
            ::|.|..|.:|.|::..|:.:.   |..|.     |.|..||:.||..:....||::|::.|||.
Zfish    90 IRIFPYGAIQFMAFDNYKKFLHTKVGISGH-----VHRLMAGSMAGMTAVICTYPLDVIRARLAF 149

  Fly   409 RRTG--QYAGIADAAVKIY-KQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNN- 469
            :.||  :|:||..|...|| |:.|:..||||.:|.|:|:.||||.....:.|||...:.:....
Zfish   150 QVTGHHRYSGIRHAFQTIYHKEGGISGFYRGLIPTIIGMAPYAGFSFFTFGTLKTLGLTHFPEQL 214

  Fly   470 -----EQPSFLVL-----LACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSS 524
                 :.|..|||     |.||..:..:.|..||||.:.|.|:|..|                |.
Zfish   215 GKPSLDNPDVLVLKTQVNLLCGGVAGAIAQTISYPLDVARRRMQLGA----------------SL 263

  Fly   525 DAHSGEETMTGLFRKIVRQEGL-TGLYRGITPNFLKVLPAVSISYVVYEYTSRAL 578
            ..|....::|...:.:..|.|: .|||||::.|:::.:|:.::::..||:..:.|
Zfish   264 PDHDKCCSLTKTLKHVYSQYGVKKGLYRGLSLNYIRCVPSQAVAFTTYEFMKQVL 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	27/90 (30%)
		Mito_carr	375..463	CDD:278578	36/90 (40%)
		Mito_carr	470..581	CDD:278578	31/115 (27%)
slc25a16	NP_991112.1	Mito_carr	21..113	CDD:278578	27/87 (31%)
		PTZ00169	25..319	CDD:240302	96/315 (30%)
		Mito_carr	120..205	CDD:278578	36/84 (43%)
		Mito_carr	227..319	CDD:278578	28/108 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940