DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and Ant2

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001259432.1	Gene:	Ant2 / 32008	FlyBaseID:	FBgn0025111	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	82/284 - (28%)
Similarity:	139/284 - (48%)	Gaps:	35/284 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 GGIAGAVSRTCTAPLDRIKVYLQVQ--------TQR-MGISECMHIMLNEGGSRSMWRGNGINVL 347
            ||::.|:::|..||::|:|:.||||        .|| .||.:|...:..|.|..|.||||..||:
  Fly    25 GGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVI 89

  Fly   348 KIAPETAFKFAAYEQMKRL-IRGDDGSRQM--SIVERFYAGAAAGGISQTIIYPMEVLKTRLA-- 407
            :..|..|..||..:..|.: :.|.|..:|.  .......:|.|||..|...:||::..:||||
  Fly    90 RYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLAAD 154

  Fly   408 LRRTG--QYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNNE 470
            :.:.|  ::.|:.|..:|:.|.:|....|||::.::.||:.|.......|:|. |.::   .|.:
  Fly   155 VGKGGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTC-RDFL---PNPK 215

  Fly   471 QPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTG 535
            ...|.|..|.....:|:..:.|||...||.|:..|:.      .:|:::..|:: ||
  Fly   216 STPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSG------LKKSEMVYKNT-AH-------- 265

  Fly   536 LFRKIVRQEGLTGLYRGITPNFLK 559
            .:..|.:|||:...::|...|.::
  Fly   266 CWLVIAKQEGIGAFFKGALSNIIR 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	31/87 (36%)
		Mito_carr	375..463	CDD:278578	27/93 (29%)
		Mito_carr	470..581	CDD:278578	21/90 (23%)
Ant2	NP_001259432.1	PTZ00169	15..305	CDD:240302	82/284 (29%)
		Mito_carr	17..111	CDD:278578	31/85 (36%)
		Mito_carr	119..215	CDD:278578	27/99 (27%)
		Mito_carr	218..307	CDD:278578	21/87 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442110
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840