DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and SPAC17H9.08

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_593578.1	Gene:	SPAC17H9.08 / 2542177	PomBaseID:	SPAC17H9.08	Length:	326	Species:	Schizosaccharomyces pombe

Alignment Length:	332	Identity:	87/332 - (26%)
Similarity:	154/332 - (46%)	Gaps:	57/332 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 WRHLV----AGGIAGAVSRTCTAPLDRIKVYLQVQ--------TQRMGISECMHIMLNEGGSRSM 338
            |..||    |||.||.|:::..|||||:|:..|..        ..|.|:.:.:..:.:..|...:
pombe    14 WEFLVKSGIAGGTAGCVAKSVVAPLDRVKILYQTNHASYRGYAYSRHGLYKAIKHIYHVYGLHGL 78

  Fly   339 WRGNGINVLKIAPETAFKFAAYEQMKR-LIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVL 402
            ::|:...:.::.|....||.||||::| |||..:....   ..||.:|:.||..|....||:|::
pombe    79 YQGHTATLYRVFPYAGIKFVAYEQVRRVLIRDPEHETH---ARRFLSGSLAGTCSVFFTYPLELI 140

  Fly   403 KTRLA-LRRTGQYAGIADAAVKIYKQEG---------------VRSFYRGYVPNILGILPYAGID 451
            :.||| :..||:...:......|:.:..               :.:||||:...:.||.||||:.
pombe   141 RVRLAYITNTGKNPTLTQVTKDIFHERDFLCNKKYPGLSRLSKICNFYRGFSVTLTGIFPYAGMS 205

  Fly   452 LAVYETL-----KRR---YIANHDNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAE 508
            ...|:..     |::   :::...::::......|.||:.:...||..|||..:.|.::|....
pombe   206 FLAYDLATDFFHKQKIDEWVSTKKSDKKLKTWPELLCGAFAGVCGQTVSYPFEVCRRKMQIGGI- 269

  Fly   509 TIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEY 573
                :|.|:.:.||.            :.:...::.|:.|.:.|:|..::||:|.||.|:.||.:
pombe   270 ----RKNKSFLRLKQ------------VVQTTYKEAGMRGFFVGLTIGYIKVIPMVSTSFFVYNH 318

  Fly   574 TSRALGI 580
            :...|||
pombe   319 SKALLGI 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	31/96 (32%)
		Mito_carr	375..463	CDD:278578	27/111 (24%)
		Mito_carr	470..581	CDD:278578	29/111 (26%)
SPAC17H9.08	NP_593578.1	Mito_carr	13..110	CDD:278578	30/95 (32%)
		Mito_carr	112..220	CDD:278578	27/110 (25%)
		Mito_carr	232..324	CDD:278578	26/108 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940