DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and slc-25A42

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_492333.1	Gene:	slc-25A42 / 172656	WormBaseID:	WBGene00009666	Length:	294	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	107/298 - (35%)
Similarity:	161/298 - (54%)	Gaps:	32/298 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 LVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMGIS-----ECMHIMLNEGGSRSMWRGNGINVLK 348
            |.||.||||:::|..|||||.|:|.||.:.| |.|     :.:.:...|.|..:::|||...:.:
Worm    18 LSAGAIAGALAKTTIAPLDRTKIYFQVSSTR-GYSFRSAIKFIKLTYRENGFFALYRGNSATMAR 81

  Fly   349 IAPETAFKFAAYEQMKRLIRGDD-GSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRTG 412
            :.|..:.:|||:||.|:|::.|: |||  :.|:|:..|:.|...:..|.||::..|.||::....
Worm    82 VVPYASMQFAAFEQYKKLLKVDENGSR--TPVKRYITGSLAATTATMITYPLDTAKARLSVSSKL 144

  Fly   413 QYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNNEQPSFLVL 477
            ||:.:....||.||:.|::..|||..|.|||::||||.....|||||..| .:|....:.|:..:
Worm   145 QYSSLKHVFVKTYKEGGIQLLYRGIYPTILGVIPYAGSSFFTYETLKIMY-RDHRGEVENSYYRM 208

  Fly   478 LACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVR 542
            | .|..:..:||..||||.:||.|:|.            .:||       ||...:..|.. |..
Worm   209 L-FGMLAGLIGQSSSYPLDIVRRRMQT------------GRIP-------SGWSPLRALIH-IYH 252

  Fly   543 QEGL-TGLYRGITPNFLKVLPAVSISYVVYEYTSRALG 579
            .||| .|||:|::.|:||...||.:|:..||.....:|
Worm   253 TEGLKRGLYKGLSMNWLKGPIAVGVSFTTYEKVLELVG 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	33/85 (39%)
		Mito_carr	375..463	CDD:278578	33/87 (38%)
		Mito_carr	470..581	CDD:278578	35/111 (32%)
slc-25A42	NP_492333.1	PTZ00169	8..271	CDD:240302	100/277 (36%)
		Mito_carr	10..100	CDD:278578	32/82 (39%)
		Mito_carr	106..198	CDD:278578	37/94 (39%)
		Mito_carr	203..291	CDD:278578	35/109 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940