DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCaMC and Slc25a41

DIOPT Version :9

Sequence 1:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_780542.1	Gene:	Slc25a41 / 103775	MGIID:	2144215	Length:	312	Species:	Mus musculus

Alignment Length:	327	Identity:	156/327 - (47%)
Similarity:	207/327 - (63%)	Gaps:	24/327 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 HSTYLDIGEDMNVPDDFTQKEMQTGLWWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMGIS 323
            |...||.||.:.||.|..::| ..|..|:.|::|.:|||||||.||||||.:||:||.:.:....
Mouse     4 HLEVLDTGEQLMVPVDVLEEE-NKGTLWKFLLSGAMAGAVSRTGTAPLDRARVYMQVYSSKSNFR 67

  Fly   324 EC---MHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKRLIRGDDGSRQMSIVERFYAG 385
            ..   :..::.|||.||:||||||||||||||.|.||:..||.|....|...|:...  ||..||
Mouse    68 NLLSGLRSLVQEGGVRSLWRGNGINVLKIAPEYAIKFSVCEQSKNFFYGVHSSQLFQ--ERVVAG 130

  Fly   386 AAAGGISQTIIYPMEVLKTRLALRRTGQYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGI 450
            :.|..:|||:|.|||||||||.||.||||.|:.|.|.:|.:::|.|:.||||:||:|||:|||..
Mouse   131 SLAVAVSQTLINPMEVLKTRLTLRFTGQYKGLLDCARQILERDGTRALYRGYLPNMLGIIPYACT 195

  Fly   451 DLAVYETLKRRYIANHDNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKR 515
            ||||||.|:..:.....:.:.||.||.|:..:.|:|.||:.||||.|||||:|||  :|:
Mouse   196 DLAVYELLQCLWQKLGRDMKDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQ--DTV----- 253

  Fly   516 KTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGI 580
                       .....||.|:|::|:.|:|..|||||:||..||||||..|||:|||...:.||:
Mouse   254 -----------EGSNPTMQGVFKRILSQQGWPGLYRGMTPTLLKVLPAGGISYLVYEAMKKTLGV 307

  Fly   581 KM 582
            ::
Mouse   308 QV 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	45/87 (52%)
		Mito_carr	375..463	CDD:278578	49/87 (56%)
		Mito_carr	470..581	CDD:278578	50/110 (45%)
Slc25a41	NP_780542.1	PTZ00169	23..305	CDD:240302	146/302 (48%)
		Mito_carr	25..116	CDD:278578	46/90 (51%)
		Solcar 1. /evidence=ECO:0000255	27..113		46/85 (54%)
		Solcar 2. /evidence=ECO:0000255	121..206		49/86 (57%)
		Mito_carr	123..209	CDD:278578	49/87 (56%)
		Mito_carr	215..306	CDD:278578	48/108 (44%)
		Solcar 3. /evidence=ECO:0000255	217..304		48/104 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0036
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333952at33208
OrthoFinder	1	1.000	-	-		FOG0000464
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X287
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.780