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Protein Alignment Smyd4-2 and SMYD3

DIOPT Version :9

Sequence 1:	NP_648574.1	Gene:	Smyd4-2 / 39414	FlyBaseID:	FBgn0036282	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_001161212.1	Gene:	SMYD3 / 64754	HGNCID:	15513	Length:	428	Species:	Homo sapiens

Alignment Length:	438	Identity:	95/438 - (21%)
Similarity:	168/438 - (38%)	Gaps:	107/438 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 RFVVANEG--------LRTGDVLLFEEPVAACLEPSYFGTHCHHCFKRLHTPVSCLHCSGIAFCS 322
            :|..|..|        ||.|::|...:|:|..:.....|..|..|.......:.|..|....:||
Human     8 KFATAKRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCS 72

  Fly   323 AQCMGEACSSYHRFECEYM---------DLMIGSGMSILCFIALRIFTQAPSLEQGLATANLLFE 378
            |:|..:|... |:.||:.:         |     .:.:|..:..::...|||..:.|.:...|..
Human    73 AKCQKKAWPD-HKRECKCLKSCKPRYPPD-----SVRLLGRVVFKLMDGAPSESEKLYSFYDLES 131

  Fly   379 HLCSHEEDRQPDDYLRRALMSGFLLRILQKSLYFGRRKTEGVN--PTAVELQVATALLGLLQVLQ 441
            ::....||::  :.||:.:|:         ..:|.|.:.:..:  |.|.:|..|.|     :|:
Human   132 NINKLTEDKK--EGLRQLVMT---------FQHFMREEIQDASQLPPAFDLFEAFA-----KVI- 179

  Fly   442 YNAHQIYQTQVTEEHRFDGSKTVYLAAGLYGTGSYFNHECWPSTACHFVGKKLVLTATRPHRANE 506
            .|:..|...::.|           :..|||.:.|..||.|.|:.:..|.|..|:|.|.|.....|
Human   180 CNSFTICNAEMQE-----------VGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGE 233

  Fly   507 LVAVNYGPIFIKNNLKERQRSLRGRYSFSCSCMACQ-------------ENW----PLLQKLDKQ 554
            .:.:.|..:.:.:  :||::.||.:|.|.|.|..||             :.|    ..|:|:::.
Human   234 ELTICYLDMLMTS--EERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEEL 296

  Fly   555 VRFW--------CTSANCSNLLKFPK---------DLAKDVRCPRCRKNISLKESVAKMIKIEEL 602
            ...|        |.:...||..:.|.         |.|.|.    |.....|:|::....:..|.
Human   297 KAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDA----CINLGLLEEALFYGTRTMEP 357

  Fly   603 YR------EAARAMEAQKTVEAIELFK-------ESLDMFFQVAALPH 637
            ||      ...|.::..| |..::|.:       ::|.:.|.:..:.|
Human   358 YRIFFPGSHPVRGVQVMK-VGKLQLHQGMFPQAMKNLRLAFDIMRVTH 404

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.