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Protein Alignment Smyd4-2 and SMYD2

DIOPT Version :9

Sequence 1:	NP_648574.1	Gene:	Smyd4-2 / 39414	FlyBaseID:	FBgn0036282	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_064582.2	Gene:	SMYD2 / 56950	HGNCID:	20982	Length:	433	Species:	Homo sapiens

Alignment Length:	415	Identity:	86/415 - (20%)
Similarity:	139/415 - (33%)	Gaps:	145/415 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 KGRFVVANEGLRTGDVLLFEEPV-AACLEPSYFGTHCHHCFKRLHTPVSCLHCSGIAFCSAQCMG 327
            |||.:.|.:..:.|| |||..|. |..|..:..|.||.:||.|......|..|....:|:.:|..
Human    17 KGRGLRALQPFQVGD-LLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQK 80

  Fly   328 EACSSYHRFECEYMDLMIGSGMSILCFIALRIFTQAPSLEQGLATANLLFEHLCSHEEDRQPDDY 392
            |.. ..|:.||..| ::.|                                      |:..|.:.
Human    81 EDW-PMHKLECSPM-VVFG--------------------------------------ENWNPSET 105

  Fly   393 LRRALMSGFLLRILQKSLYFGRRKTEGVNPTAVELQVATALLGLLQVLQYNAH---------QIY 448
            :|      ...|||.|         :.::|.      .|....||.|.::.:|         .:.
Human   106 VR------LTARILAK---------QKIHPE------RTPSEKLLAVKEFESHLDKLDNEKKDLI 149

  Fly   449 QTQVTEEHRF--------DGSKTV-------------------YLAAGLYGTGSYFNHECWPSTA 486
            |:.:...|.|        |....|                   :|.:.::...:..||.|.|:..
Human   150 QSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVI 214

  Fly   487 CHFVGKKLVLTATRPHRANELVAVNYGPIFIKNNLKERQRSLRGRYSFSCSCMACQENWPLLQKL 551
            ..:.|....:.|.:..:..|.|..:|  |.:....::|...||..|.|:|.   |||
Human   215 VTYKGTLAEVRAVQEIKPGEEVFTSY--IDLLYPTEDRNDRLRDSYFFTCE---CQE-------- 266

  Fly   552 DKQVRFWCTSANCSNLLKFPKDLAK-DVR----CPRCRKNISLKESVAKMIK-----IEELYREA 606
                   ||:.:        ||.|| ::|    .|:.       |::..|::     ||| :|.|
Human   267 -------CTTKD--------KDKAKVEIRKLSDPPKA-------EAIRDMVRYARNVIEE-FRRA 308

  Fly   607 ARAMEAQKTVEAIELFKESLDMFFQ 631
            .......:.:|..||.:|.:...|:
Human   309 KHYKSPSELLEICELSQEKMSSVFE 333

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.