DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd4-2 and CG18213

DIOPT Version :9

Sequence 1:	NP_648574.1	Gene:	Smyd4-2 / 39414	FlyBaseID:	FBgn0036282	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_650589.2	Gene:	CG18213 / 42055	FlyBaseID:	FBgn0038470	Length:	879	Species:	Drosophila melanogaster

Alignment Length:	389	Identity:	84/389 - (21%)
Similarity:	138/389 - (35%)	Gaps:	143/389 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 LFSAQRRAQADKLYL-MSGSGDG----------EESRELLQQALMAANLAVMRAPDRNADPVLDE 137
            ||....|...||::| .|...:|          .:|..:|:..|.:.:..:.|||  :|.|
  Fly    36 LFLKILRKTTDKVFLDFSEVAEGCLNISKKCMNMKSPTVLKMTLQSLDEIICRAP--SASP---- 94

  Fly   138 GLTLALAYRSRASILIRLGEGEAALNDLKLAINFGLELKSSVDYYLKMAKAYAVMGEPARAEISL 202
              |...|..:|:.:.|:..:...|.|||.              ||..:        :||     |
  Fly    95 --TCVDAIMARSVLYIKNNQNTTACNDLL--------------YYESL--------DPA-----L 130

  Fly   203 KIAEKMPGCDATHIALC------------RKELSSVKPKPKEAT----SEQVPQLAHGES-AELV 250
            |.||   |...:.|..|            :.:||.||...::.|    ||..|.||..|. .|.:
  Fly   131 KTAE---GTIISQILHCICLFVNREYEASKDKLSVVKGLIEDGTLADRSEVSPFLALIEQHEERI 192

  Fly   251 GASKV----VRLVETK----------------------------DKGRFVVANEGLRTGDVLLFE 283
            ..:::    .:.|:|:                            :|...|.|:..:..|:::|.|
  Fly   193 NQARINVEFCKKVQTENFVPFKGFKLTRKIPFASQACDYSEKSIEKSGGVFASCDVPKGEIVLVE 257

  Fly   284 EPVAACLEPSYFG-----THCHHCFKRLHTPVSCLHCSGIAFCSAQCMGEACSSYHRFECEYMDL 343
            .||       ||.     .:|..|........:|.:|...::||..|| ::.:..|::||
  Fly   258 NPV-------YFQFSAPFLNCELCGVHQQQLYTCDNCRYRSYCSKSCM-KSDAEVHQYEC----- 309

  Fly   344 MIGSGMSILCFIALRIFTQAPSLEQGLATANLLFEHLCSHEEDRQPDDYLRRAL----MSGFLL 403
             .|..:.::           |.||     ||:||...|      :..:|:..|:    |.|.:|
  Fly   310 -YGYKIGLI-----------PMLE-----ANMLFRLFC------EAGEYILPAIVDYAMDGGIL 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-2	NP_648574.1	TPR_11	142..205	CDD:290150	13/62 (21%)
		zf-MYND	299..338	CDD:280009	9/38 (24%)
		SET	<474..513	CDD:279228
CG18213	NP_650589.2	zf-MYND	271..309	CDD:280009	9/38 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452064
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46165
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030