Protein Alignment Smyd4-2 and dao

DIOPT Version :10

• Sequence 1: NP_648574.1
• Gene: Smyd4-2 / 39414
• FlyBaseID: FBgn0036282
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_609742.1
• Gene: dao / 34891
• FlyBaseID: FBgn0028862
• Length: 882
• Species: Drosophila melanogaster
• Alignment Length: 731
• Identity: 153/731 - (20%)
• Similarity: 244/731 - (33%)
• Gaps: 229/731 - (31%)

  Fly    55 LSIFSDREVCDPVLGVLEHVQPVFKQKDALFSAQRRAQADKLYLMSGSGDGEESRELLQQA---- 115
            |.|.|.....:|||....||...|:.               |...:|....||....|::|
  Fly   127 LGISSPTTTKEPVLDFRPHVLKWFQH---------------LRHQTGHFKSEEESRRLREAGNDS 176

  Fly   116 -------LMAANL---AVMRAPDRNADPVLDEGLTLALAYRSRASILIRLGEGEAALNDLKLAIN 170
                   |.|::|   |:..||.||.       |..|||:.:|:.:|...|....:.:|...|::
  Fly   177 YRKERHPLKASDLFTEAIFLAPARNT-------LAAALAHANRSLVLFDCGLYAESYDDCLCALD 234

  Fly   171 FGLELKSSVDYYLKMAKAYAVMGEPARAEISLKIAEKMPGCDATHIALCRKELSSVKPKPKEATS 235
            .|..     :.||.:.|.       .:|..:||:         .:.|||.:.|       .|...
  Fly   235 LGYP-----EEYLPLIKL-------RQAACALKL---------RNFALCEEHL-------HELLH 271

  Fly   236 EQVPQLAHGESAELVGASKVVRL------------VETKDKGRFVVA----NEGLRT-----GDV 279
            .::.|:....:.||....:|:::            ::..|...|.:|    :..|.|     .:.
  Fly   272 IELNQVFEARTHELWHQCEVLKVERFEMAVQTGDDLDINDSKAFEIAWLDNSSSLHTTRAVAKNA 336

  Fly   280 LLFEEPVAACLEPSYFGTHCHHCFKRLHTPVSCLHCSG--IAFCSAQCMGEACSSYHRFEC--EY 340
            |:||.. |..:.||.....|.:|......|..|::||.  :.:||.||..:. ::.|..||  ..
  Fly   337 LIFESE-AVAMVPSGNCRVCDYCGITQFIPFPCIYCSNRLVVYCSRQCRFKH-AAIHAVECFGHQ 399

  Fly   341 MDLM--IGS--GMSILCFIALR-IFTQAPSL-----------------------EQGLA-TANLL 376
            ::|.  .|.  ||..|..:|.| :.|..|.|                       .|.:| :|.|.
  Fly   400 IELFESFGEVFGMPRLLQLAFRMLITGLPELLGHCRKKPTLSKLWSAINGGLQERQDIAYSAVLR 464

  Fly   377 FEHLCSHEEDRQPDDYLRRALMSGFLLRILQKSLYFGRRKTEGVNPTAV-------ELQVATALL 434
            .|.|   :|:|..|..:..||.:..|...|.|...|..:..:.: |||.       ||..|..|:
  Fly   465 LERL---KEERPTDTVIALALAAHILSIYLSKCTTFFDQLEKSL-PTASRMSSAEWELLCAALLM 525

  Fly   435 GLLQVLQY---------------------NAHQIYQT--QVTEEHRFDGSKTVYLAAGLYGTGSY 476
            ..:..|::                     |..|::..  ::.|.|       ::|.||.....||
  Fly   526 RHIGQLRHRSLTACRSFVLPADPHVFSPLNEFQLWAAPMRLQEGH-------LHLLAGEVAVVSY 583

  Fly   477 ---------FNHECWPSTACHFVGKKLVLTATRPHRANELVAVNYGPIFIKNNLKERQRSLRGRY 532
                     ..|.|..:....|.|:.:...|.....|...:   |. .|...|.::..|..|.:.
  Fly   584 SVYPDTLNLCRHSCSSTICAKFSGRTVTALALLDLPAGSGI---YN-CFAGGNFQQLPREERTKQ 644

  Fly   533 ----SFSCSCMACQENWPLLQKLDKQV----RFWCTSANC-----SNLLKFPKDL---------- 574
                ...|.|.|||     |...|.|.    |:.|.:.||     .|.|.....|
  Fly   645 LLESGIRCHCNACQ-----LTHSDDQFHKFHRYRCDNPNCMEIFTPNALPHAPSLRWWLSEEYTQ 704

  Fly   575 -----AKDVRCPRCRKNISLKESVAKMIKIEELYREAARAMEAQKTVEAIELFKESLDMFFQVAA 634
                 |..:.||.|          .:..|:|..:......::.:...|..:|:          ||
  Fly   705 PEFNGADLIMCPHC----------GEYQKLEWFWAFTTSLIDCELIEERCKLY----------AA 749

  Fly   635 LPHKDTIVAQQSLHKC 650
            :...:..:  ..||:|
  Fly   750 IERAENQL--MDLHEC 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-2	NP_648574.1	BepA	87..205	CDD:443813	30/131 (23%)
		SET_SMYD4	249..541	CDD:380934	81/388 (21%)
		zf-MYND	299..338	CDD:460312	11/40 (28%)
dao	NP_609742.1	TPR repeat	200..235	CDD:276809	11/41 (27%)
		TPR repeat	243..270	CDD:276809	9/49 (18%)
		SET	<459..657	CDD:394802	43/212 (20%)