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Protein Alignment Smyd4-2 and Smyd4

DIOPT Version :9

Sequence 1:	NP_648574.1	Gene:	Smyd4-2 / 39414	FlyBaseID:	FBgn0036282	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_001096081.1	Gene:	Smyd4 / 319822	MGIID:	2442796	Length:	799	Species:	Mus musculus

Alignment Length:	716	Identity:	155/716 - (21%)
Similarity:	258/716 - (36%)	Gaps:	159/716 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DKWLRNYFGKLKSNAARVLSIFSDREVCD----PVLGVLEHVQPVF-KQKDALFSAQRRAQADKL 96
            |:|......|..|....|....|..|...    |...:|:....:| |:..:.:|.::...|...
Mouse     6 DEWKSYLLKKWASLPKSVQDTISTAETLSDIFLPSSSLLQPEDEMFLKELSSSYSVEKDNDAPLF 70

  Fly    97 YLMSGSGDGEESRELLQQALMAANLAVMRAPDRNADPVLDEGLTLALAYRSRASILIRLGEGEAA 161
            |...|:...:| :|....|::.:. .|..:.....|        ::|.|.:|::.|..||:.||.
Mouse    71 YREEGNRKFQE-KEYTDAAVLYSK-GVSHSRPNTED--------ISLCYANRSAALFHLGQYEAC 125

  Fly   162 LNDLKLAINFGLELKSSVDYYLKMAKAYAVMGEPARAEISLKIAEKMPGCDATHIALCRKELSS- 225
            |.|:..|...|...:......::..:....:|....|..::...|.......|.:      |||
Mouse   126 LKDIVEAGMHGYPERLQPKMMVRKTECLVNLGRLQEARQTISDLESSLTAKPTLV------LSSY 184

  Fly   226 -----------VKPKPKEATSEQVP--------QLAHG-ESAELVGASKVVRLVETKDKGRFVVA 270
                       :|.:.||...|.:|        .:|.| |:.::.|||..|.|.....|||.:||
Mouse   185 QILQRNVQHLKIKIQEKETLPEPIPAALTNAFEDIALGEENTQISGASLSVSLCTHPLKGRHLVA 249

  Fly   271 NEGLRTGDVLLFEEPVAA------------CLEPSY------FGTHCHHCFKRLHTPVSCLHCSG 317
            .:.:..|::|:.|:...:            |||..:      ...:||.|.|.....|.|..||.
Mouse   250 TKDILPGELLVKEDAFVSVLIPGEMPRPHHCLENKWDTRVTSGDLYCHRCLKHTLATVPCGSCSY 314

  Fly   318 IAFCSAQCMGEACSSYHRFECEYMDLMIGSGMSILCFIALRI----------------------- 359
            ..:||.:||.:|...||..||....|::..|  :.|.:|||:
Mouse   315 AKYCSQECMQQAWDLYHSTECSLGGLLLTLG--VFCHVALRMTLLARFEDVDRVVRMLCDEVGST 377

  Fly   360 ----------------FTQAPSLEQGL----------------ATANLLFEHLCSHEEDRQPDDY 392
                            .:|..|.|:..                :..|.:|. |..|.|...|:..
Mouse   378 DTCLPESKNLVKAFDYTSQGESEEKSKIGEPPIPGCNVNGKYGSNYNAIFS-LLPHTEKHSPEHR 441

  Fly   393 LRRALMSGFLLRILQ----KSLYFGRRKTEGVNP-TAVELQV--ATALLGLLQVLQYNAHQIYQT 450
            ...|:....|.|.|:    ::......|.:.|.| ...:|.|  |..|..:|| ||.||..|  |
Mouse   442 FICAISVSALCRQLKADSVQAQTLKSPKLKAVTPGLCADLTVWGAAMLRHMLQ-LQCNAQAI--T 503

  Fly   451 QV----TEEHRFDGSKTVYLAAGLYGTGSYFNHECWPSTACHFVGKKLVLTATRPHRANELVAVN 511
            .:    :.|.....|:.:.||.|::...|..||.|.|:|:..|.|....:.|.:.....:.:...
Mouse   504 SICHTGSNESIITNSRQIRLATGIFPVVSLLNHSCRPNTSVSFTGTVATVRAAQRIAKGQEILHC 568

  Fly   512 YGPIFIKNNLKERQRSLRGRYSFSCSCMACQENWPLLQKLDKQVRFWCTSA----------NCSN 566
            |||...:..:.|||:.|..:|.|.|.|.||...........:...|.|.:.          :|||
Mouse   569 YGPHESRMGVAERQQRLSSQYFFDCRCGACHAETLRAAAAPRWEAFCCKTCRALMQGNDVLSCSN 633

  Fly   567 LLKFPKDLAKDVRCPRCRKNISLKESVAKMIKIEELYREAARAMEAQKTVEAIELF---KESLDM 628
                          ..|..::|..:.|:::..:::....|.:.:...|..:||:..   :|:.:.
Mouse   634 --------------ESCTNSVSRDQLVSRLQDLQQQVCMAQKLLRTGKPEQAIQQLLRCREAAES 684

  Fly   629 F 629
            |
Mouse   685 F 685

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.