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Protein Alignment Smyd4-2 and SMYD1

DIOPT Version :9

Sequence 1:	NP_648574.1	Gene:	Smyd4-2 / 39414	FlyBaseID:	FBgn0036282	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_938015.1	Gene:	SMYD1 / 150572	HGNCID:	20986	Length:	490	Species:	Homo sapiens

Alignment Length:	397	Identity:	86/397 - (21%)
Similarity:	142/397 - (35%)	Gaps:	83/397 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 VGASKVVRLVETKDKGRFVVANEGLRTGDVLLFEEPVAACLEPSYFGTHCHHCFKRLHTPVSCLH 314
            :|..:.|.:...:.|||.:.|.:.....|::..|...:|.:..|.....||.||||......|..
Human     3 IGRMENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQEKLHRCGQ 67

  Fly   315 CSGIAFCSAQCMGEACSSYHRFECEYM---DLMIGSGMSILCFIALRIFTQAPSLEQG-LATANL 375
            |....:|...|..:|..: |:.||..:   ..:....:.:...|..|:..:...|.:| |.:.:.
Human    68 CKFAHYCDRTCQKDAWLN-HKNECSAIKRYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDD 131

  Fly   376 LFEHLCSHEEDRQPDDYLRRALMSGFLLRILQKSLYFGRRKTEGVNPTAVELQVATALLGLLQVL 440
            |..|:....|:.|.|   .|..:..||.....:|..|             .:|..:.:.|   |:
Human   132 LQNHVEHFGEEEQKD---LRVDVDTFLQYWPPQSQQF-------------SMQYISHIFG---VI 177

  Fly   441 QYNAHQIYQTQVTEEHRFDGSKTVYLAAGLYGTGSYFNHECWPSTACHF-------------VGK 492
            ..|...:...:        |.:.|  ..|::......||:|||:....|             ...
Human   178 NCNGFTLSDQR--------GLQAV--GVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQM 232

  Fly   493 KLVLTATRPHRANELVAVNYGPIFIKNNLKERQRSLRGRYSFSCSCMACQENWPLLQKLDKQVRF 557
            ::.|.|.......|.:.|:|  |...|..:||:|.|:.:|.|.|:|..||      :|| |...|
Human   233 RIELRALGKISEGEELTVSY--IDFLNVSEERKRQLKKQYYFDCTCEHCQ------KKL-KDDLF 288

  Fly   558 WCTSAN-------CSNLLKFPKDLAKDVRCPRCRKNISLKESVAKMIKIEELYREAAR----AME 611
            .....|       ...:::|.||..:.:...|.                |.||.|..:    .:|
Human   289 LGVKDNPKPSQEVVKEMIQFSKDTLEKIDKARS----------------EGLYHEVVKLCRECLE 337

  Fly   612 AQKTVEA 618
            .|:.|.|
Human   338 KQEPVFA 344

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.