Protein Alignment CG32104 and Rpap1

DIOPT Version :10

• Sequence 1: NP_648573.2
• Gene: CG32104 / 39413
• FlyBaseID: FBgn0052104
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_796268.3
• Gene: Rpap1 / 68925
• MGIID: 1916175
• Length: 1409
• Species: Mus musculus
• Alignment Length: 1448
• Identity: 369/1448 - (25%)
• Similarity: 548/1448 - (37%)
• Gaps: 364/1448 - (25%)

  Fly     1 MFKKLKPGESEEDVLRMAAEFNAERAKDPNFQPAAAFVRMDKAPKKSMFAQ-RREQAKLGRV--- 61
            |..:.||||||.|:||..::| .|....|..|......|...||...:..| .|:...|..:
Mouse     2 MLSRPKPGESEVDLLRFQSQF-LEAGAAPAVQLVKGSRRHGDAPPDRLPPQDHRDVVMLDNLPDL 65

  Fly    62 -TSTTEKNEEQIQPVPKEIIPQIPTSVPKER----GSHVSQVLLDEIQENILGDVKGSKMDPSSL 121
             .:......::.:|.|...:|.  ...|:||    ..|::.| |.:|.|.....|..:...||.:
Mouse    66 PPALLPAPAKRARPSPGHPLPH--DEDPEERLNRHDQHITAV-LSKIVERDTSSVTVTLPVPSGV 127

  Fly   122 GNVLGELVERTEGTRRSAFP---------ETKNVDSSKPLSIFAKQLLGAKSSTKEKSNKVSDFP 177
                             |||         :.|...|.| .||||:::...:.|....::.....|
Mouse   128 -----------------AFPPVFHRSQERQVKPAASGK-RSIFAQEIAARRVSGNRVTSAEQVVP 174

  Fly   178 RNDT--------SSIIKD------------------------AKLGKE----LHQENLNVLKQMN 206
            ..||        :...:|                        :|:.::    :|:||:..|:.|:
Mouse   175 SLDTPEGAVPCETPSFRDRSNQLPGRSHGFHRPNLVTGKGLRSKVAEQEVQTIHEENVARLQAMD 239

  Fly   207 EQDILTEKERLLASLDPSLIALLSKKRQT-----TPNSKPPNPNSPKVIEAPPMPAQSTRAQDPQ 266
            .::||.|:::|||.|||||:|.|....|.     |..:|..:|..|.|:.....|..|||.::|:
Mouse   240 PEEILKEQQQLLAQLDPSLVAFLRSHSQVQEQTGTKATKKQSPKRPSVLVTKEEPVTSTRTREPR 304

  Fly   267 I-----------------SSLTDGNPAIELLQESDKGNWLNFNLVEEHKLAWMRDIPAKISELKP 314
            .                 ..|....||::|.....| :||:.:.||..||.|.:|:| .:...:.
Mouse   305 TGDKLEEKPEATVEDKMEDKLQPRTPALKLPMTPSK-DWLHMDTVELDKLHWTQDLP-PLRRQQT 367

  Fly   315 GEQFNARFDWKGVLLPHTLKDQDASKQIDERELYLHGEEADRPGYALQELFRLARSTVLQQRLSA 379
            .|:..|||..:|.||   ..|.|....:.   |:.|||||:|.||:|||||.|.||.|.|||..|
Mouse   368 QERMQARFSLQGELL---APDVDLPTHLG---LHHHGEEAERAGYSLQELFHLTRSQVSQQRALA 426

  Fly   380 FGAIAGIFSIYNQG-FYDQ----VLSLPISKIF-FLLRFGLDDNAPAQLEVVSRALSNLFYNETD 438
            ...::.|......| |.|:    ||.|.:...| |||||.|||...:.:....|||..|.....|
Mouse   427 LQVLSQIVGRAQAGEFGDRLVGSVLRLLLDAGFLFLLRFSLDDRVDSVIAAAVRALRTLLVAPGD 491

  Fly   439 EVLLDHVHDNAYCHWQPTLEVLGNGSDGNGEDTDTNSIAFLQRYMKLLTTSKSVRAEVDEDESES 503
            |.|||...  ::.|......::.:..|...||.|..           |.|.|..|...:|.   |
Mouse   492 EELLDRTF--SWYHGASVFPLMPSQDDKEDEDEDEE-----------LETEKVKRKTPEEG---S 540

  Fly   504 RTSMDDFQLAETDLMDCLLRTNILQRIRFILVSVKPDNSTVESCLKLLIRIARTSTKVARQLANE 568
            |...|   ||..|::..||.||:|.|:|::|....|..|.:...|.:|||:||.|.:.|.::...
Mouse   541 RPPPD---LARHDVIKGLLATNLLPRLRYVLEVTCPGPSVILDILAVLIRLARHSLESAMRVLEC 602

  Fly   569 SHLIDTLFKHFLPSS------SGSNQFYGQPQVLFLKLIRVLICHHLDIAKGISKGVLI-TRLQQ 626
            ..|::|:.:.|||:|      ..:...|..|....:||:|||.....:||..:..|..: :||.:
Mouse   603 PRLMETIVQEFLPTSWSPIGVGPTPSLYKVPCASAMKLLRVLASAGRNIAARLLSGFDVRSRLCR 667

  Fly   627 Y-------LFLQDNKVQMVRIQIEALRILRCLLLLGIVDRDIFRQFLPALRQLLDWHGNHCAFDG 684
            :       |.|...:.::  :..||.|:.......| ...|::|:..|.|.:.|.......:...
Mouse   668 FIAEAPHDLALPPEEAEI--LTTEAFRLWAVAASYG-QGGDLYRELYPVLLRALQTLPTELSAHP 729

  Fly   685 VGGSGLVRQHAAALLVALV-------------ASGESGAC-----------DVEGQKLLVE---- 721
            :  ..|..|..|||...|.             |||.:.:|           .|.|.|.|||
Mouse   730 L--QPLAMQRVAALFTLLTQLTLAASSIPPEPASGPAESCVPAIPSSVTWTQVSGLKPLVEPCLK 792

  Fly   722 ----------------PLNNCCC----GWMHAASR------------VAKIKDFSQMTLLS---- 750
                            |:.:.|.    .:..|.||            :.::.|.|.:.|||
Mouse   793 QTLKFLPRPDVWNALGPVPSACLLFLGAYYQAWSRQSHLCPEDWLQDMERLLDESLLPLLSQPPL 857

  Fly   751 -----------------------------AALYAVGWFSRNSLLGTTSFLPFLR---SILPKFVQ 783
                                         .:|...|.....|:.|:.|..|||.   |::...||
Mouse   858 GSLWDSLRDCSPLCNPLSCASNPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLINTLVQ 922

  Fly   784 S------------------SGFIACVHDLVKGSIMLRRPIDRRHVHAPLPNVGAVLMHDYGPQLV 830
            |                  :.|:.||                    ||.|          .|||.
Mouse   923 SHKGLCGQLSAVLTAPGLQNYFLQCV--------------------APAP----------APQLT 957

  Fly   831 VSETYPVHLLSNLWALLAISLDSGEKPLFEALIQPAVLEPLAEYLRQLSTQLNRVLATNFFARSE 895
            ....:.:|   :.:.|..:.|....|   .|.:||   ||.|      ||.|:..:|
Mouse   958 PFSAWALH---HEYHLQYLVLSFAHK---AATLQP---EPAA------STALHHAVA-------- 999

  Fly   896 LRFIHQLLTTDGIEIYLKRQQMLQLVYNYLCCLSTAHATQIKSIFERFIFNGDFVKLDESS---- 956
            |..:.:||  .|.| ||.::.:|..|:.......:|......:.|      .|.:.|..|.
Mouse  1000 LVLLSRLL--PGSE-YLAQELLLSCVFRLEFLPESASGGPEAADF------SDGLSLGSSGDPQC 1055

  Fly   957 --LKLLQQSCLEMVYPHI----IADNSEPSLSLSYTQA-------------------PILPTDWP 996
              ..||.|:|.::  |.|    :|..|....||..:||                   |:|.||||
Mouse  1056 RRGALLVQACRDL--PSIRSCYLAHCSPARASLLSSQALYCGELLRVSSLLLPVPKEPLLATDWP 1118

  Fly   997 FFQLRVILSNYLQNVQQRPAAIHSENQVVLMTLTFVRQLER---EGLQIVSPLEKLMYLMIAFMG 1058
             ||..:.|.:...:....|.|..:.. |.:..|.:|..||.   |.|..|.|..:|..||..::.
Mouse  1119 -FQPLIHLYHRASDTPSGPPAADTVG-VAMRVLQWVLVLESWRPEVLWAVPPAARLARLMCVYLV 1181

  Fly  1059 PDSQFLAPDLHELLRDCLMDFYRENAAHEFDFDAELVDKARFEPLYYLFVEHFEAASYGDELFSS 1123
            ....|....:..|:...|....|.........|..|.....|..||..|::||||.|:||.||.:
Mouse  1182 DSELFRETPIQRLVAALLARLCRPQVLPNLKLDCPLPGLTSFPDLYASFLDHFEAVSFGDHLFGA 1246

  Fly  1124 LVLVPLAQKYDNKWRRRLWSEHVQAVRFINCDESMLMGGLFAYLEPVEEEPSLVKLYGDALAQKM 1188
            |||:||.:::....|..|:.|||..:|.:....:.|...|..|.||.|:...|::||..||....
Mouse  1247 LVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLPVPLECYTEPAEDSLPLLQLYFRALVTGT 1311

  Fly  1189 VRPG--SIAYRIAQHHFN 1204
            :|..  .|.|.:|..|.|
Mouse  1312 LRARWCPILYTVAVAHVN 1329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32104	NP_648573.2	RPAP1_N	192..234	CDD:462539	18/45 (40%)
		RPAP1_C	319..391	CDD:462538	31/71 (44%)
Rpap1	NP_796268.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..95		11/62 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..210		1/20 (5%)
		RPAP1_N	225..270	CDD:462539	19/44 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	265..322		11/56 (20%)
		RPAP1_C	372..437	CDD:462538	31/70 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..547		12/52 (23%)