Protein Alignment Ncc69 and B0303.11

DIOPT Version :10

• Sequence 1: NP_001261758.1
• Gene: Ncc69 / 39410
• FlyBaseID: FBgn0036279
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_001299855.1
• Gene: B0303.11 / 176222
• WormBaseID: WBGene00015131
• Length: 927
• Species: Caenorhabditis elegans
• Alignment Length: 1062
• Identity: 269/1062 - (25%)
• Similarity: 463/1062 - (43%)
• Gaps: 233/1062 - (21%)

  Fly   214 WI--KGVLVRCLLNIWGVMLFLRLSWVVGQAGVIEGFVLILTTTAVTTITALSMSAISTNGVIKG 276
            |:  |.|.::|:..:..|:|.||.|.:|.:||.....:|:..|..|:.:|..|...:.:....:.
 Worm    18 WMNWKDVFLKCVQPMLAVVLLLRFSSIVDEAGFTTTIILVFFTFLVSLVTGWSACTVVSRKSSEV 82

  Fly   277 GGTYYMISRSLGPEFGGSIGLIFSLANAVACAMYVVGFCESMLAMMTTFGWEIIDGGVQDVRIIG 341
            |....|::.| ..||..|..:|:.....||.:.::....|::|.:.:||..|::||...|:|::.
 Worm    83 GFVKTMLAYS-STEFAISFSIIYLFCLLVATSTFLTSAAEAVLHIFSTFSLELLDGATHDLRLVS 146

  Fly   342 CITILLLLIIVVVGMEWEAKAQIGLLIILLVAIGDFVIGSFIGPKSDAEMAKGFLGYNATLFKNN 406
            .:..|:.|.:.:|........:..:..:..:||.                    |..::.:|:
 Worm   147 SVLSLITLALCMVRNRNARFVRTFIFALTCIAIA--------------------LQLSSVMFR-- 189

  Fly   407 LFADYRPEKGGIQH---------DFFSVFAIFFPAATGILAGANISGDLKDPQKSIPKGTILAIV 462
             :.:|:..:...::         :..::||..||||...|...||...|   |.:.|:|.::||.
 Worm   190 -YGEYQLRRVSDRNAMIPSPPNEEISTIFAQLFPAAMCGLTILNIGSKL---QNTAPRGALIAIA 250

  Fly   463 ITTGTYLIMVLQCGATV--------ARDATGNLSDVVNGTFAFLDCQPGECNYGLQNSFQVIELV 519
            ::...|       ||..        ||.:|.|              ..|...|   |.|  :..:
 Worm   251 VSACFY-------GAAAMLDYVEFFARTSTSN--------------STGSAEY---NEF--LSYI 289

  Fly   520 SAFGPLIYAGCYAATLSSALASLVSAPKVFQALCKDELYPKIVWFAKGYGKNNEPVRGYVLTFII 584
            ....|:......|..| ||:::|..|..:.|:|.:......|:|.|||:|:.:.|:|..:|...:
 Worm   290 YTTVPMAIVITLACVL-SAVSTLKYAAVILQSLGRSNQCRCILWLAKGFGERDIPIRCLLLLSTV 353

  Fly   585 ACAFILIGELNLIAPLISNFFLAAYMLINFSTFHASLAKP-VGWRPTF-------------KYYN 635
            ......||..:::....:.|:|.||.|.||..|...|:.| :...||.             .|.|
 Worm   354 QILVSAIGSYDILCIPTTVFYLFAYALFNFYVFLVKLSDPEIPSPPTLLSLAISAACFIASLYTN 418

  Fly   636 MWLSLLGAILCVAVMFLISWATALITFAAVLALYLIVAYRKPDVNWGSTTQAQTYKNALMSVQQL 700
            ..|:|.     :|.:|.||:.:         .||:|...|..|   |.......|.:.|..:.:|
 Worm   419 RHLALF-----IASIFAISYCS---------LLYIIRRERNED---GEECPKSMYSSVLEQMHEL 466

  Fly   701 NNVEEHVKNYRPQILVLSGLPNTRPVLVDLAYMLTKNLSLLVCGHVLKGSSSQ--------KY-- 755
            ....:..:::.||||:|||.|..||.|||.|:.:|:..|||:||:::...|::        :|
 Worm   467 QQEPDSRRHFHPQILLLSGSPAARPGLVDFAHSITRGKSLLICGYIIPKISNKVEQPMTWTEYLM 531

  Fly   756 ------RTYL-----QERAGNWFRKHRVKGFYALVDGEDFESGTRALMQATGIGKLKPNIILMGY 809
                  |:||     .::..:|.|...|..|.|.:.......|...|:|..|:|:|:|||:::||
 Worm   532 QQSPCSRSYLLQLKIDKQINDWLRAREVNAFGAAICCTKQAEGANILLQTAGLGRLRPNILMLGY 596

  Fly   810 KTDWQTCDHKELDQYFNVMHKALDMYLSVAILRVPQGLDCSQVLGSQDGWKTVSDVPRTLQPNES 874
            ||.|:....:.:.:|:.::..|.|..:.|.|.|                             ||:
 Worm   597 KTGWEKLSKESISEYYGMLSNAFDKQVGVIIFR-----------------------------NEA 632

  Fly   875 SG-DLQAVDSSVR-NG--------LSGSIDSLSRNVS-----QEDRNRNQLVHSEQNSLKIVKLR 924
            || |   |.||:| ||        |:..:||.:..::     ::|..|.:|:::.:.....|...
 Worm   633 SGFD---VTSSIRKNGAPINDDEDLAEYVDSATPKLADQGSQKKDVPRGKLLNTFRKMSMAVNKD 694

  Fly   925 FKQGLRRMRSWPGAASSTSDLSFIAGNQSKDVSGMPDPLDAKSANLVSNSLRKSKLKHDDPASLY 989
            .:.|.||        |::|...|    |..|...:.:|                    |.
 Worm   695 LESGGRR--------STSSSTRF----QVIDKHSISEP--------------------DQ----- 722

  Fly   990 KGPGGAELPKEVLADLTQFTRKRSHAVIDVWWLYDDGGLTLLLPYIISTRRTW-QSCKLRVYALA 1053
                     |.::|.:.:|.::..:|.|||:||.:.||||:|.||:::...:: :...:||:...
 Worm   723 ---------KIIMAQMFRFRKRIPNARIDVFWLREAGGLTMLAPYLLTQAGSFLEGAHIRVFTKT 778

  Fly  1054 N--KNSELEFEQRSMASLLSKFRIDYSDLTLIPDITKKP-QETSTQFFNELIKDFVVTEKDGENG 1115
            :  .|..:..||::||::|.||.||.|||.::|:.:|.| ::|..:|..::.|..|.|...||
 Worm   779 DGKDNKRINEEQKNMAAILRKFHIDSSDLHILPEFSKPPCKQTYDEFRAKIDKYKVETSSSGE-- 841

  Fly  1116 TSSRATLNEDDALITDDDLLAVQDKTNRYLRLREYLREQSTKSDLVVMTLPMPRKNIVSAPLYMA 1180
                    ..|....::.:..:::||..:||..|.:||.|:.:||:|.|||..|..|.| |:|:.
 Worm   842 --------PVDGSFDNNQIFNLREKTRSFLRASELIREHSSDADLIVCTLPSARPEIPS-PIYLG 897

  Fly  1181 WLESLSRDMPPFLFVRGNQTSV 1202
            |::.|||..||...|||||.|:
 Worm   898 WIDMLSRQTPPTCLVRGNQVSM 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ncc69	NP_001261758.1	AA_permease_2	155..1207	CDD:459263	269/1062 (25%)
B0303.11	NP_001299855.1	AA_permease_2	2..916	CDD:459263	266/1057 (25%)
		SLC12	490..919	CDD:460955	142/517 (27%)