Protein Alignment Ncc69 and slc12a9

DIOPT Version :10

• Sequence 1: NP_001261758.1
• Gene: Ncc69 / 39410
• FlyBaseID: FBgn0036279
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: XP_031755483.1
• Gene: slc12a9 / 100493856
• XenbaseID: XB-GENE-5943241
• Length: 900
• Species: Xenopus tropicalis
• Alignment Length: 1102
• Identity: 277/1102 - (25%)
• Similarity: 458/1102 - (41%)
• Gaps: 272/1102 - (24%)

  Fly   155 TREALPRLDNYRNMMSIQAAYRPTLDELHNATLVGKNTHSLTRNQDPESGILNGVLKFGWIKGVL 219
            |.|:.|.| :||.......|..|.     :::..|.:..::....:|.        |.....||:
 Frog     3 TSESSPLL-HYRLFSVSDGALGPP-----DSSPCGTDAVAVGTGTNPR--------KLSTFFGVV 53

  Fly   220 VRCLLNIWGVMLFLRLSWVVGQAGVIEGFVLILTTTAVTTITALSMSAISTNGVIKGGGTYYMIS 284
            |..:|:::.:::|:|:.:|||.||:::..|::....|:..:|.||:.||||||.::|||.|:|||
 Frog    54 VPTVLSMFSIVVFMRIGFVVGHAGLLQSLVMLFVAYAIIWLTVLSVCAISTNGAVQGGGAYFMIS 118

  Fly   285 RSLGPEFGGSIGLIFSLANAVACAMYVVGFCESMLAMMTTFGWEIIDGGVQDVR----------I 339
            |:|||||||||||:|.|||..||.:||:|..|   |::..||.: ..|....:|          :
 Frog   119 RTLGPEFGGSIGLMFYLANVFACGVYVLGLVE---AVLDVFGRD-PSGPTDSLRSLPQGYGYNFL 179

  Fly   340 IGCITILLLLIIVVVGMEWEAKAQIGLLIILLVAIGDFVIGSFIGPK---------SDAEMAKGF 395
            ...|.:||.:.|.:||....::|...:.:::.|.:...:| ||:..:         .:......:
 Frog   180 YASIILLLCMAICLVGASIYSQASFFIFLLVFVVLLTILI-SFLAVRPLTVTIRHGGNVTFTGVY 243

  Fly   396 LGYNATLFKNNLFADYRPE--KGGIQHDFFSVFAIFFPAATGILAGANISGDLKDPQKSIPKGTI 458
            .|.|::...:||.|||..:  .|.:. :|.:|||:.|...|||:||.|:||:||.|.:|||.|||
 Frog   244 TGINSSTLHDNLQADYSLDYTTGNLM-NFATVFAVMFNGCTGIMAGCNLSGELKQPSRSIPIGTI 307

  Fly   459 LAIVITTGTYLIM----VLQCGATVARDATGNLSDVVNGTFAFLDCQPGECNYGLQNSFQVIELV 519
            :|::||...|||:    .|.|..|:.|:                       :||.   |:.|.:
 Frog   308 IAVIITFFVYLILFIFTALTCDRTLLRE-----------------------DYGF---FRPINI- 345

  Fly   520 SAFGPLIYAGCYAATLSSALASLVSAPKVFQALCKDELYPKIVWFAKGYGKNNEPVRGYVLTFII 584
              :.|.:..|.||.:||:::::|:.|.::..||.||:|:..::..||...|...|....:.|:.:
 Frog   346 --WPPFVLIGVYATSLSASMSTLIGASRILHALAKDDLFGVLLAPAKLVSKGGNPWGAVIYTWAL 408

  Fly   585 ACAFILIGELNLIAPLISNFFLAAYMLINFSTFHASLAKPVGWRPTFKYYNMWLSLLGAILCVAV 649
            ....:|.|:||.||.:::.|:|.||..|:.:......|....:||||:.::....|||.:.|:.:
 Frog   409 VQLVLLAGKLNTIAGIVTVFYLIAYAAIDLACLALEWASAPNFRPTFRLFSWHTCLLGILSCLVM 473

  Fly   650 MFLISWATALITFAAVLALYLIVAYRKPDVNWGSTTQAQTYKNALMSVQQLNNVEEHVKNYRPQI 714
            ||||:.|.|..:...:|.|...:.:|....:||..:||..:......:..|:..::|||.:||||
 Frog   474 MFLINPAYASGSIVLLLLLLGSIHFRSSSSSWGYISQALIFHQVRKYLLLLDVRKDHVKFWRPQI 538

  Fly   715 LVLSGLPNTRPVLVDLAYMLTKNLSLLVCGHVLKGSSSQKYRTYLQERAGNWFR---KHRVKGFY 776
            |::...|.|...|:.....|.|. .|.:.|||..|.........:|.....|..   |..||.|.
 Frog   539 LLMVSNPRTSCQLIKFVNDLKKG-GLYILGHVETGDLDTLPSDPVQTHYSFWLSLVDKLNVKAFV 602

  Fly   777 ALVDGEDFESGTRALMQATGIGKLKPNIILMGYKTDWQTCDHKELDQYFNVMHKALDMYLSVAIL 841
            .|........|.:.|::.||:|.:|||.:::|:..|....|:...||.|:......|...
 Frog   603 DLTLCPSVRQGAQHLLRITGLGGMKPNTLVLGFYDDASPDDYFLQDQLFSPSLSPKDDAF----- 662

  Fly   842 RVPQGLDCSQVLG----SQDGWKTVSDVPRTLQPNESSGDLQAVDSSVRNGLSGSIDSLS--RNV 900
                |:|.:.:..    ::|     .:.||.|..|:.              ::...|:|.  :|:
 Frog   663 ----GVDATSLQAHFPPARD-----PETPRLLPANDY--------------VAMICDALKMHKNI 704

  Fly   901 SQEDRNRNQLVHSEQNSLKIVKLRFKQGLRRMRSWPGAASSTSDLSFIAGNQSKDVSGMPDPLDA 965
            ... ||...||..|.:|..:.          :..|                          |||
 Frog   705 VLA-RNFPLLVRPEASSPAMY----------IDVW--------------------------PLD- 731

  Fly   966 KSANLVSNSLRKSKLKHDDPASLYKGPGGAELPKEVLADLTQFTRKRSHAVIDVWWLYDDGGLTL 1030
                                                      ..|.::.|.:||..|:     .|
 Frog   732 ------------------------------------------LLRPQASAYVDVCSLF-----LL 749

  Fly  1031 LLPYIISTRRTWQSCKLRVYALANKN-------------SELEFEQRSMASLLSKFRIDYSDLTL 1082
            .:..|::...:|:..:|||:......             :|.:|.:     ||||.||
 Frog   750 QMACILNMAASWRRFQLRVFLCVESRGGGGSDGASGWIAAEAKFRE-----LLSKLRI------- 802

  Fly  1083 IPDITKKPQETSTQFFNELIK----DFVVTEKDGENGTSSRATLNEDDALITDDDLLAVQDKTNR 1143
                            ..||:    |.|...: |.|.        |..||             ||
 Frog   803 ----------------RALIRVVAWDRVAALR-GPNA--------EGQAL-------------NR 829

  Fly  1144 YLRLREYLR--------EQSTKSDLVVMTLPMPRKNIVSAPLYMAWLESLSRDMPPFLFVRG 1197
            .....|||:        |...::.:..:.||.|..:......|:..|::|:..:.|.|.:.|
 Frog   830 EPISCEYLKAANRAVEEEGGAETGVRFLYLPRPPADPALHQRYLEELDTLTGGLGPTLLIHG 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ncc69	NP_001261758.1	AA_permease_2	155..1207	CDD:459263	277/1102 (25%)
slc12a9	XP_031755483.1	AA_permease_2	43..891	CDD:459263	267/1054 (25%)