Protein Alignment CrzR and RXFP3

DIOPT Version :9

• Sequence 1: NP_001261755.1
• Gene: CrzR / 39409
• FlyBaseID: FBgn0036278
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_057652.1
• Gene: RXFP3 / 51289
• HGNCID: 24883
• Length: 469
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 97/453 - (21%)
• Similarity: 158/453 - (34%)
• Gaps: 115/453 - (25%)

  Fly   119 LLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTW--SAIYSLMFHLSIAD---VLVTWFC 178
            |:.|....|.|| .|.||||.::.:        .|...|  |:|...:.:|::.|   ||...|.
Human    83 LISVVYWVVCAL-GLAGNLLVLYLM--------KSMQGWRKSSINLFVTNLALTDFQFVLTLPFW 138

  Fly   179 IIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKR---- 239
            .:..|   ...:|...:..||:|.:....::|.|.:.|..:.|.|:.:|...:||......
Human   139 AVENA---LDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGD 200

  Fly   240 -CHRLLGGT------------YILSLVLSLPQFFIFHVARGPFVEEFYQCVTH------GFYTAD 285
             |.|.||.:            :.|:.:.|||. .||........||.  |:..      |.....
Human   201 CCGRSLGDSCCFSAKALCVWIWALAALASLPS-AIFSTTVKVMGEEL--CLVRFPDKLLGRDRQF 262

  Fly   286 WQEQMYATFTLVFTFLLPLCILFGTYMSTFRTISSSEKMFQGSKLANYSTAKLPTQTNRQRLIHK 350
            |. .:|.:..::..|:|||.|:...|:...|.|  :::...|:|.........||..:.:||
Human   263 WL-GLYHSQKVLLGFVLPLGIIILCYLLLVRFI--ADRRAAGTKGGAAVAGGRPTGASARRL--- 321

  Fly   351 AKMKSLRISVVIIIAFLICWTPYYVM---MIMFMFLNPDKRLGDDLQDAIFF------------- 399
              .|..:...:::::|.:||.|...:   .|:..|            :|:.|
Human   322 --SKVTKSVTIVVLSFFLCWLPNQALTTWSILIKF------------NAVPFSQEYFLCQVYAFP 372

  Fly   400 ----FGMSNSLVNPLIYGAFHLCPGKGGKSSGGGGNNNAYSLNRGDSQRTPSMLTAVTQVDGTGG 460
                ...|||.:||::|     |                 .:.|...:...|:|..:     ...
Human   373 VSVCLAHSNSCLNPVLY-----C-----------------LVRREFRKALKSLLWRI-----ASP 410

  Fly   461 SSRQMRAFRQQSYYRSSSNGTAGPGAAPFKEQVGLLHVGPGNGTPGGSVSSGATPQLIRKGSA 523
            |...||.|...:.......|...|.......:..||:.     .||..|.||....|:...||
Human   411 SITSMRPFTATTKPEHEDQGLQAPAPPHAAAEPDLLYY-----PPGVVVYSGGRYDLLPSSSA 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	38/154 (25%)
		7tm_1	135..412	CDD:278431	70/324 (22%)
RXFP3	NP_057652.1	7tm_1	98..389	CDD:278431	70/324 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010