DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CrzR and Galr1

DIOPT Version :9

Sequence 1:	NP_001261755.1	Gene:	CrzR / 39409	FlyBaseID:	FBgn0036278	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_037090.2	Gene:	Galr1 / 50577	RGDID:	2656	Length:	346	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	93/352 - (26%)
Similarity:	143/352 - (40%)	Gaps:	82/352 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 SLAHTNSRHEAPPMAEQVPEHVMDHAPQLSRSGLLKVYVLAVMAL---FSLLGNLLTIWNIYKTR 147
            :|:..|.....|| ||..|         |...|:.....|.|..|   ..:|||.|.|     |.
  Rat     7 NLSEGNGSDPEPP-AEPRP---------LFGIGVENFITLVVFGLIFAMGVLGNSLVI-----TV 56

  Fly   148 ISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLS 212
            ::|.......|.....:.:|||||:....|||..:|.......|:.....||.:..|...|:.:|
  Rat    57 LARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVS 121

  Fly   213 TYVLVLIGVDRWIAVKYPMKSLNMAKRCHRLLGGTYI--LSLVLSLPQFFIFHVARGPFVEEFYQ 275
            .:.|..:.|||::|:.:..:|.::....:.|||..:|  ||:.::.|      ||       :||
  Rat   122 IFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASP------VA-------YYQ 173

  Fly   276 CVTH-----GFYTADWQEQM----YATFTLVFTFLLPLCILFGTYMSTFRTISSSEKMFQGSKLA 331
            .:.|     .|....|..|:    |...|.||.:||||.::...|                :|:.
  Rat   174 RLFHRDSNQTFCWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCY----------------AKVL 222

  Fly   332 NYSTAKLPTQTNRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMMIMFMF----LNPDKRLGDD 392
            |:...||   .|..:....:|.|:.:..:|:::.|.|.|.|::|:.:...|    |.|
  Rat   223 NHLHKKL---KNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPLTP------- 277

  Fly   393 LQDAIFFF-------GMSNSLVNPLIY 412
               |.|||       ..|||.|||:||
  Rat   278 ---ASFFFRITAHCLAYSNSSVNPIIY 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	38/137 (28%)
CrzR	NP_001261755.1	7tm_1	135..412	CDD:278431	78/298 (26%)
Galr1	NP_037090.2	7tm_1	49..301	CDD:278431	78/298 (26%)
Galr1	NP_037090.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	326..346
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100